Informed Consent
Item
signed informed consent
boolean
C0021430 (UMLS CUI [1])
Able to swallow oral medication
Item
able to swallow an oral medication
boolean
C2712086 (UMLS CUI [1,1])
C0175795 (UMLS CUI [1,2])
Cardiac ejection fraction | Echocardiography
Item
cardiac ejection fraction within the institutional range of normal as measured by echocardiogram
boolean
C0232174 (UMLS CUI [1])
C0013516 (UMLS CUI [2])
Renal function | Liver function
Item
adequate kidney and liver function
boolean
C0232804 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
Bone Marrow function
Item
adequate bone marrow function
boolean
C0005953 (UMLS CUI [1,1])
C0031843 (UMLS CUI [1,2])
Tumor tissue Available Testing
Item
tumor tissue available for testing
boolean
C0475358 (UMLS CUI [1,1])
C0470187 (UMLS CUI [1,2])
C0039593 (UMLS CUI [1,3])
Adjuvant therapy | Neoadjuvant Therapy | Anthracycline Antibiotics | Anthraquinones | Doxorubicin Cumulative Dose | Epirubicin Cumulative Dose | Mitoxantrone Cumulative Dose
Item
prior adjuvant or neoadjuvant therapy is permitted with an anthracycline or anthracenedione-containing regimen however, subjects must have had cumulative doses of less than 360 mg/m2 of doxorubicin, 720 mg/m2 of epirubicin, or 72 mg/m2 of mitoxantrone
boolean
C0677850 (UMLS CUI [1])
C0600558 (UMLS CUI [2])
C0003234 (UMLS CUI [3])
C0003174 (UMLS CUI [4])
C0013089 (UMLS CUI [5,1])
C2986497 (UMLS CUI [5,2])
C0014582 (UMLS CUI [6,1])
C2986497 (UMLS CUI [6,2])
C0026259 (UMLS CUI [7,1])
C2986497 (UMLS CUI [7,2])
HER2/NEU Overexpression Tumor tissue | HER2/Neu Status Unknown
Item
no her2/neu overexpression in tumor tissue tested or status unknown if tissue has never been tested
boolean
C3810543 (UMLS CUI [1,1])
C1514559 (UMLS CUI [1,2])
C0475358 (UMLS CUI [1,3])
C2348910 (UMLS CUI [2])
Prior Therapy Advanced breast cancer | Prior Therapy Breast Carcinoma Metastatic
Item
prior treatment regimens for advanced or metastatic breast cancer.
boolean
C1514463 (UMLS CUI [1,1])
C3495917 (UMLS CUI [1,2])
C1514463 (UMLS CUI [2,1])
C0678222 (UMLS CUI [2,2])
C0036525 (UMLS CUI [2,3])
Pregnancy | Breast Feeding
Item
pregnant or lactating
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Condition Affecting drug absorption
Item
conditions that would effect the absorption of an oral drug
boolean
C0348080 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0678745 (UMLS CUI [1,3])
Communicable Disease
Item
active infection
boolean
C0009450 (UMLS CUI [1])
Metastatic malignant neoplasm to brain
Item
brain metastases
boolean
C0220650 (UMLS CUI [1])
Endothelial Growth Factor Receptor Inhibitors
Item
treatment with egfr (endothelial growth factor receptor) inhibitor.
boolean
C2267120 (UMLS CUI [1])
HypersensitivityTaxol | Hypersensitivity Taxol Excipient
Item
known hypersensitivity to taxol or excipients of taxol
boolean
C0020517 (UMLS CUI [1,1])
C0678133 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0678133 (UMLS CUI [2,2])
C0015237 (UMLS CUI [2,3])
Peripheral Neuropathy | CTCAE Grades
Item
peripheral neuropathy of grade 2 or greater is not permitted
boolean
C0031117 (UMLS CUI [1])
C1516728 (UMLS CUI [2])
Cardiovascular Disease Severe | Cardiovascular Disease Requirement Medical Device
Item
severe cardiovascular disease or cardiac disease requiring a device.
boolean
C0007222 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0007222 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0025080 (UMLS CUI [2,3])
Disease Serious Interferes with patient safety | Disease Serious Interferes with Informed Consent | Mental disorder Interferes with patient safety | Mental disorder Interferes with Informed Consent
Item
serious medical or psychiatric disorder that would interfere with the patient's safety or informed consent.
boolean
C0012634 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C1113679 (UMLS CUI [1,4])
C0012634 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C0521102 (UMLS CUI [2,3])
C0021430 (UMLS CUI [2,4])
C0004936 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C1113679 (UMLS CUI [3,3])
C0004936 (UMLS CUI [4,1])
C0521102 (UMLS CUI [4,2])
C0021430 (UMLS CUI [4,3])