Age
Item
1. 18 years of age.
boolean
C0001779 (UMLS CUI [1])
Systolic hypertension disease stage
Item
2. patients with stage ii systolic hypertension
boolean
C0221155 (UMLS CUI [1,1])
C0699749 (UMLS CUI [1,2])
Gender Serum pregnancy test negative | Postmenopausal state | Hysterectomy | Tubal Ligation | Childbearing Potential Contraceptive methods | Informed Consent
Item
3. if female, must have negative serum pregnancy test at screening and be either post-menopausal, had a hysterectomy or tubal ligation at least 6 months before consent or if of childbearing potential, must practice approved measures of birth control throughout study.
boolean
C0079399 (UMLS CUI [1,1])
C0430061 (UMLS CUI [1,2])
C0232970 (UMLS CUI [2])
C0020699 (UMLS CUI [3])
C0520483 (UMLS CUI [4])
C3831118 (UMLS CUI [5,1])
C0700589 (UMLS CUI [5,2])
C0021430 (UMLS CUI [6])
Hypertensive Encephalopathy | Cerebrovascular accident | Transient Ischemic Attack
Item
1. hypertensive encephalopathy, stroke or transient ischemic attack (tia) within the past 6 months.
boolean
C0151620 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
C0007787 (UMLS CUI [3])
Myocardial Infarction | Coronary revascularisation Transluminal Percutaneous | Coronary Artery Bypass Surgery | Angina, Unstable
Item
2. history of myocardial infarction, percutaneous transluminal coronary revascularization, coronary artery bypass graft, and/or unstable angina pectoris within the past 6 months.
boolean
C0027051 (UMLS CUI [1])
C0877341 (UMLS CUI [2,1])
C0522520 (UMLS CUI [2,2])
C0522523 (UMLS CUI [2,3])
C0010055 (UMLS CUI [3])
C0002965 (UMLS CUI [4])
Hypertension, severe | Diastolic blood pressure | Systolic Pressure
Item
3. severe hypertension (dbp greater than or equal to 110 mm hg or sbp > 200 mm hg).
boolean
C4013784 (UMLS CUI [1])
C0428883 (UMLS CUI [2])
C0871470 (UMLS CUI [3])
Secondary hypertension | Kidney Diseases | Pheochromocytoma | Cushing's disease
Item
4. history of secondary hypertension including renal disease, phaeochromocytoma, or cushing's disease.
boolean
C0155616 (UMLS CUI [1])
C0022658 (UMLS CUI [2])
C0031511 (UMLS CUI [3])
C0221406 (UMLS CUI [4])
Diabetes Mellitus, Insulin-Dependent | Resting Bradycardia Symptomatic Evidence of | Congestive heart failure | Heart valve disease Hemodynamic Significant
Item
5. type i diabetes mellitus. 6. evidence of symptomatic resting bradycardia, congestive heart failure, or hemodynamically significant cardiac valvular disease.
boolean
C0011854 (UMLS CUI [1])
C3278174 (UMLS CUI [2,1])
C0231220 (UMLS CUI [2,2])
C0332120 (UMLS CUI [2,3])
C0018802 (UMLS CUI [3])
C0018824 (UMLS CUI [4,1])
C0019010 (UMLS CUI [4,2])
C0750502 (UMLS CUI [4,3])
Heart Block | First degree sinoatrial block | Wolff-Parkinson-White Syndrome | Sick Sinus Syndrome | Atrial Fibrillation | Atrial Flutter
Item
7. presence of heart block greater than first degree sinoatrial block, wolff-parkinson-white syndrome, sick sinus syndrome, atrial fibrillation, or atrial flutter.
boolean
C0018794 (UMLS CUI [1])
C3854673 (UMLS CUI [2])
C0043202 (UMLS CUI [3])
C0037052 (UMLS CUI [4])
C0004238 (UMLS CUI [5])
C0004239 (UMLS CUI [6])
Laboratory Results Clinical Significance
Item
8. laboratory test values considered clinically significant by the investigator.
boolean
C1254595 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
Liver disease Evidence of | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Serum total bilirubin measurement
Item
9. evidence of liver disease as indicated by sgot or sgpt and/or total bilirubin > 3 times the upper limit of normal.
boolean
C0023895 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C1278039 (UMLS CUI [4])
Pregnancy | Breast Feeding
Item
10. pregnant or lactating females.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Malignant Neoplasms | Squamous cell carcinoma of skin | Basal cell carcinoma
Item
11. patients with malignancy during the past 5 years excluding squamous cell or basal cell carcinoma of the skin.
boolean
C0006826 (UMLS CUI [1])
C0553723 (UMLS CUI [2])
C0007117 (UMLS CUI [3])