Adult | Age
Item
adult male or female, age 18 or older
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
pegylated interferon alfa | Ribavirin | Combined Modality Therapy Hepatitis C, Chronic
Item
planning to receive any brand of pegylated interferon/ribavirin combination therapy for chronic hcv (hepatitis c virus)
boolean
C0907160 (UMLS CUI [1])
C0035525 (UMLS CUI [2])
C0009429 (UMLS CUI [3,1])
C0524910 (UMLS CUI [3,2])
Chronic liver disease | Hepatitis C, Chronic
Item
chronic liver disease other than chronic hcv
boolean
C0341439 (UMLS CUI [1])
C0524910 (UMLS CUI [2])
Liver disease Advanced | Ascites | Bleeding varices | Encephalopathy Spontaneous
Item
evidence of advanced liver disease such as a history of or presence of ascites, bleeding varices, or spontaneous encephalopathy
boolean
C0023895 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C0003962 (UMLS CUI [2])
C0333106 (UMLS CUI [3])
C0085584 (UMLS CUI [4,1])
C0205359 (UMLS CUI [4,2])
Organ Transplantation
Item
a history of organ transplantation
boolean
C0029216 (UMLS CUI [1])
medical condition Pre-existing Interferes with Study Subject Participation Status | Epilepsy Requirement Pharmaceutical Preparations | Injury of central nervous system Major | Accidental event Causing Loss of consciousness | Accidental event Causing Personality change
Item
any known preexisting medical condition that could interfere with the patient's participation in the protocol, including: *active seizure disorders requiring medication; *history of major cns (central nervous system) trauma (as suggested by accident or other event leading to loss of consciousness, personality changes, etc)
boolean
C3843040 (UMLS CUI [1,1])
C2347662 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C2348568 (UMLS CUI [1,4])
C0014544 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0013227 (UMLS CUI [2,3])
C1264238 (UMLS CUI [3,1])
C0205164 (UMLS CUI [3,2])
C1690974 (UMLS CUI [4,1])
C0678227 (UMLS CUI [4,2])
C0840361 (UMLS CUI [4,3])
C1690974 (UMLS CUI [5,1])
C0678227 (UMLS CUI [5,2])
C0240735 (UMLS CUI [5,3])
medical condition Requirement systemic steroids chronic | Adrenal Cortex Hormones | Injection of steroid
Item
any medical condition requiring, or likely to require during the course of the study, chronic systemic administration of steroids (e.g. oral or injection).
boolean
C3843040 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C2825233 (UMLS CUI [1,3])
C0205191 (UMLS CUI [1,4])
C0001617 (UMLS CUI [2])
C1261311 (UMLS CUI [3])
Able to read Insufficient | Able to write Insufficient | Patient Self-Report Completion Unable
Item
inability to read and write at a level sufficient to complete self-report forms
boolean
C0586740 (UMLS CUI [1,1])
C0231180 (UMLS CUI [1,2])
C0584993 (UMLS CUI [2,1])
C0231180 (UMLS CUI [2,2])
C0681906 (UMLS CUI [3,1])
C0205197 (UMLS CUI [3,2])
C1299582 (UMLS CUI [3,3])
Compliance behavior Limited
Item
history of significant non-compliance with medical treatments and appointments
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
Antidepressive Agents Dose Full | Pharmaceutical Preparations Affecting Significant Depressive Symptoms
Item
patients currently, or within the last three months, on a full therapeutic dose of antidepressant medication, or a dose of other medication such that it may significantly affect depressive symptomatology
boolean
C0003289 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0443225 (UMLS CUI [1,3])
C0013227 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0750502 (UMLS CUI [2,3])
C0086132 (UMLS CUI [2,4])
Depressive disorder | Beck depression inventory
Item
patients with active depression in the previous 3 months and/or those with bdi (beck depression inventory)-ii greater than or equal to 15 at the time of study entry.
boolean
C0011581 (UMLS CUI [1])
C0451022 (UMLS CUI [2])
Bipolar Disorder
Item
patients with bipolar disorder or history of bipolar disorder
boolean
C0005586 (UMLS CUI [1])
Psychotic symptom | Schizophrenia
Item
patients with active psychotic symptoms or diagnosis of schizophrenia in the previous 3 months
boolean
C0871189 (UMLS CUI [1])
C0036341 (UMLS CUI [2])
Substance Use Disorders | intravenous drug Abuse | inhaled substance Abuse | sustained remission
Item
active substance abuse, such as alcohol (greater than 80 gm/day), iv (intravenous) drugs, and inhaled drugs. if the patient has a history of substance abuse, in order to be considered for inclusion into the protocol, the patient must have been in a sustained remission for at least 6 months
boolean
C0038586 (UMLS CUI [1])
C0683092 (UMLS CUI [2,1])
C1546935 (UMLS CUI [2,2])
C0683094 (UMLS CUI [3,1])
C1546935 (UMLS CUI [3,2])
C0814128 (UMLS CUI [4])
Opiate Substitution Treatment | Drug addiction therapy - methadone
Item
patients receiving opiate agonist therapy (e.g., methadone maintenance therapy) within the past year, unless a program of testing for continued substance abuse is initiated (testing at entry and then randomly at least every 2-3 months) and the patient is withdrawn from study for any violation.
boolean
C2936530 (UMLS CUI [1])
C0588202 (UMLS CUI [2])