Gender, Age
Item
will be women aged 18 years and over
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Good health as determined by history and physical examination
Item
will be in good health apart from asthma or obesity as determined by history and physical examination (no other condition that could influence the proposed tests).
boolean
C0018759 (UMLS CUI [1])
C0031809 (UMLS CUI [2])
non smokers or ex-smokers for more than six months
Item
all will be non smokers or ex-smokers for more than six months with a smoking history of no more than 10 pack- years (i.e., one pack per day or its equivalent for 10 years.)
boolean
C0543414 (UMLS CUI [1])
severe asthma treated with corticosteroids
Item
subjects will have a physician's made diagnosis of severe asthma and treated with corticosteroids.
boolean
C0581126 (UMLS CUI [1])
C0001617 (UMLS CUI [2])
Informed consent
Item
subjects who are, in the opinion of the investigator, mentally or legally incapacitated thus preventing informed consent from being obtained.
boolean
C0021430 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
Comorbidity
Item
subjects having a co-existing illness that precludes them from the trial.
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
Pregnancy or lactation
Item
pregnancy or lactation
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Contraindication to prednisone treatment
Item
contraindication to the prednisone treatment.
boolean
C1301624 (UMLS CUI [1,1])
C0032952 (UMLS CUI [1,2])