Major Depressive Disorder
Item
primary diagnosis of major depressive disorder (mdd)
boolean
C1269683 (UMLS CUI [1])
Single major depressive episode
Item
must have met dsm-iv criteria for current major depressive episode for at least 8 weeks but no long than 2 years.
boolean
C0024517 (UMLS CUI [1])
Hamilton rating scale for depression
Item
ham-d17 total score of >17 at screening and baseline.
boolean
C0451203 (UMLS CUI [1])
Severity of illness Score
Item
severity of illness score of >4 at screening and baseline.
boolean
C0521117 (UMLS CUI [1,1])
C0449820 (UMLS CUI [1,2])
Sexual functioning Discuss Willing
Item
willing to discuss sexual functioning with investigator or designee.
boolean
C0278092 (UMLS CUI [1,1])
C2584313 (UMLS CUI [1,2])
C0600109 (UMLS CUI [1,3])
Sexual activity Causing Orgasm Frequency
Item
sexual activity that leads to orgasm at least every 2 weeks.
boolean
C0036864 (UMLS CUI [1,1])
C0678227 (UMLS CUI [1,2])
C0029260 (UMLS CUI [1,3])
C0376249 (UMLS CUI [1,4])
Bipolar I disorder | Bipolar II disorder | Schizophrenia | Psychotic Disorder
Item
past or current dsm-iv diagnosis of bipolar disorder i or ii, schizophrenia or another psychotic disorder(s).
boolean
C0853193 (UMLS CUI [1])
C0236788 (UMLS CUI [2])
C0036341 (UMLS CUI [3])
C0033975 (UMLS CUI [4])
Panic Disorder | Obsessive-Compulsive Disorder | stress related disorder
Item
primary dsm-iv diagnosis or received treatment for panic disorder, obsessive compulsive disorder or post stress disorder within previous 12 months.
boolean
C0030319 (UMLS CUI [1])
C0028768 (UMLS CUI [2])
C0599909 (UMLS CUI [3])
Risk homicidal | At risk for suicide Serious | Homicide attempt | Suicide attempt | homicidal
Item
poses a homicidal or serious suicidal risk, have made an attempt within months prior to screening or who has ever been homicidal.
boolean
C0035647 (UMLS CUI [1,1])
C0745031 (UMLS CUI [1,2])
C0563664 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C0277662 (UMLS CUI [3])
C0038663 (UMLS CUI [4])
C0745031 (UMLS CUI [5])
Myocardial Infarction
Item
myocardial infarction with 1 year of screening.
boolean
C0027051 (UMLS CUI [1])
Bupropion Hydrochloride | venlafaxine
Item
taken ibupropion hydrochloride or venlafaxine in the last 6 months.
boolean
C0700563 (UMLS CUI [1])
C0078569 (UMLS CUI [2])
Illicit drug use Urine test Positive | Substance Use Disorders
Item
positive urine test for illicit drug use or alcohol or substance abuse within the past 12 months.
boolean
C0281875 (UMLS CUI [1,1])
C0042014 (UMLS CUI [1,2])
C1514241 (UMLS CUI [1,3])
C0038586 (UMLS CUI [2])
Psychotherapy
Item
psychotherapy within 3 months.
boolean
C0033968 (UMLS CUI [1])
Pregnancy
Item
pregnant.
boolean
C0032961 (UMLS CUI [1])
Electroconvulsive Therapy | Transcranial magnetic stimulation
Item
electroconvulsive therapy or transcranial magnetic stimulation within 6 months prior of screening.
boolean
C0013806 (UMLS CUI [1])
C0436548 (UMLS CUI [2])
Atrial hypertrophy by EKG | Atrial hypertrophy Evidence Clinical | Ventricular hypertrophy on ECG | Ventricular hypertrophy Evidence Clinical
Item
ecg or clinical evidence of atrial or ventricular hypertrophy.
boolean
C0232311 (UMLS CUI [1])
C0340278 (UMLS CUI [2,1])
C0332120 (UMLS CUI [2,2])
C0205210 (UMLS CUI [2,3])
C1856342 (UMLS CUI [3])
C0340279 (UMLS CUI [4,1])
C0332120 (UMLS CUI [4,2])
C0205210 (UMLS CUI [4,3])