Multiple myeloma
Item
histologically confirmed multiple myeloma
boolean
C0026764 (UMLS CUI [1])
Candidate for stem cell transplantation
Item
candidate for autologous or allogeneic stem cell transplantation within 1 to 3 months after study treatment
boolean
C1504389 (UMLS CUI [1])
Measurable disease
Item
measurable disease, defined as serum monoclonal protein ≥ 1 g/dl or urinary light chain excretion = 500 mg/24 hours
boolean
C2984963 (UMLS CUI [1])
C2827353 (UMLS CUI [2,1])
C2827741 (UMLS CUI [2,2])
Malignant cns disease
Item
no malignant cns disease
boolean
C0348374 (UMLS CUI [1])
Patient characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
Life expectancy
Item
life expectancy ≥ 6 months
boolean
C0023671 (UMLS CUI [1])
Absolute neutrophil count
Item
absolute neutrophil count ≥ 1,000/mm³
boolean
C0948762 (UMLS CUI [1])
Platelet count
Item
platelet count > 50,000/mm³
boolean
C0032181 (UMLS CUI [1])
Creatinine
Item
creatinine ≤ 2 mg/dl
boolean
C0201976 (UMLS CUI [1])
Hepatic function
Item
hepatic function ≤ 2 times upper limit of normal
boolean
C0023901 (UMLS CUI [1])
DLCO
Item
dlco ≥ 50%
boolean
C1516251 (UMLS CUI [1])
Active infection
Item
no active infection
boolean
C0009450 (UMLS CUI [1])
Hypersensitivity to rabbit proteins
Item
no hypersensitivity to rabbit proteins
boolean
C0020517 (UMLS CUI [1,1])
C3887509 (UMLS CUI [1,2])
Hyperviscosity syndrome
Item
no symptomatic hyperviscosity syndrome
boolean
C0221030 (UMLS CUI [1])
Pregnancy test
Item
negative pregnancy test
boolean
C0032976 (UMLS CUI [1])
Concurrent therapy
Item
prior concurrent therapy:
boolean
C0009429 (UMLS CUI [1])
Prior chemotherapy
Item
more than 28 days since prior chemotherapy, including prednisone (20 mg equivalent/day)
boolean
C0392920 (UMLS CUI [1])
Anti-thymocyte globulin
Item
no prior anti-thymocyte globulin
boolean
C0003442 (UMLS CUI [1])
Concurrent radiotherapy
Item
no concurrent radiotherapy
boolean
C0009429 (UMLS CUI [1,1])
C1522449 (UMLS CUI [1,2])