Outpatient with nonpsychotic, unipolar major depressive disorder (mdd)
Item
currently an outpatient with nonpsychotic, unipolar major depressive disorder (mdd)
boolean
C0029921 (UMLS CUI [1,1])
C0743076 (UMLS CUI [1,2])
C1269683 (UMLS CUI [1,3])
Hamilton rating scale for depression
Item
score of 14 or greater on the 17-item hamilton rating scale for depression (ham-d17)
boolean
C0451203 (UMLS CUI [1])
Antidepressant treatment is deemed appropriate
Item
antidepressant treatment is deemed appropriate by the study clinician
boolean
C0003289 (UMLS CUI [1,1])
C3640049 (UMLS CUI [1,2])
Contraception
Item
willing to use an effective form of contraception throughout the study
boolean
C0700589 (UMLS CUI [1])
Mentally or legally incapacitated
Item
mentally or legally incapacitated
boolean
C1321605 (UMLS CUI [1])
Bipolar disorder, schizophrenia, schizoaffective disorder, mdd with psychotic features, or dementia
Item
lifetime history of bipolar disorder, schizophrenia, schizoaffective disorder, mdd with psychotic features, or dementia
boolean
C0005586 (UMLS CUI [1])
C0036341 (UMLS CUI [2])
C0036337 (UMLS CUI [3])
C0270458 (UMLS CUI [4])
C0497327 (UMLS CUI [5])
Anorexia nervosa, bulimia nervosa, or obsessive compulsive disorder
Item
patients currently suffering from anorexia nervosa, bulimia nervosa, or obsessive compulsive disorder
boolean
C0003125 (UMLS CUI [1])
C2267227 (UMLS CUI [2])
C0028768 (UMLS CUI [3])
Substance abuse disorder
Item
history of substance abuse disorder within 6 months prior to study entry
boolean
C0038586 (UMLS CUI [1])
Suicidal ideation
Item
current suicidal ideation that would make outpatient treatment unsafe
boolean
C0424000 (UMLS CUI [1])
past medication response that may make escitalopram or sertraline treatment unsafe or inappropriate
Item
past medication response that may make escitalopram or sertraline treatment unsafe or inappropriate (e.g., previous intolerance or lack of response to either medication)
boolean
C1319171 (UMLS CUI [1,1])
C1099456 (UMLS CUI [1,2])
C1319171 (UMLS CUI [2,1])
C0074393 (UMLS CUI [2,2])
history of failed treatment
Item
history of a failed treatment with escitalopram (40 mg or more) or sertraline (200 mg or more) during the current depressive episode
boolean
C0438286 (UMLS CUI [1,1])
C1099456 (UMLS CUI [1,2])
C0438286 (UMLS CUI [2,1])
C0074393 (UMLS CUI [2,2])
Contraindication to treatment with Escitalopram or Setraline
Item
any medical conditions that would make treatment with escitalopram or sertraline medically inadvisable
boolean
C1301624 (UMLS CUI [1,1])
C1099456 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0074393 (UMLS CUI [2,2])
Comorbidity
Item
unstable medical illness
boolean
C0009488 (UMLS CUI [1])
Psychiatric illness likely to require inpatient treatment
Item
unstable psychiatric illness likely to require inpatient treatment within the 6 months following study entry
boolean
C0004936 (UMLS CUI [1,1])
C1708385 (UMLS CUI [1,2])
History of seizures, brain surgery, skull fracture, significant head trauma, or previous abnormal eeg
Item
history of seizures, brain surgery, skull fracture, significant head trauma, or previous abnormal eeg
boolean
C0036572 (UMLS CUI [1])
C0195775 (UMLS CUI [2])
C0037304 (UMLS CUI [3])
C0018674 (UMLS CUI [4])
C0013819 (UMLS CUI [5])
Pregnant or planning to become pregnant
Item
pregnant or plans to become pregnant within the 12 months following study entry
boolean
C0032961 (UMLS CUI [1])
C2081645 (UMLS CUI [2])
Breast feeding
Item
breastfeeding
boolean
C0006147 (UMLS CUI [1])