Adenocarcinoma of rectum Resectable | Adenocarcinoma of rectum Resectable potential
Item
patients with resectable or potentially resectable adenocarcinoma of the rectum
boolean
C0149978 (UMLS CUI [1,1])
C1514888 (UMLS CUI [1,2])
C0149978 (UMLS CUI [2,1])
C1514888 (UMLS CUI [2,2])
C3245505 (UMLS CUI [2,3])
TNM clinical staging | Loop colostomy - stoma Patient need for
Item
clinical stage t2 n1-2 or t3-4 n0-2 (patients who require diverting loop colostomy are eligible)
boolean
C3258246 (UMLS CUI [1])
C0444911 (UMLS CUI [2,1])
C0686904 (UMLS CUI [2,2])
Age | ECOG performance status
Item
age greater than 18 years, ecog performance status < 2 (appendix, section 13.1)
boolean
C0001779 (UMLS CUI [1])
C1520224 (UMLS CUI [2])
Adenocarcinoma | Biopsy | Tumor margin Upper Distance from anal verge | Rigid sigmoidoscopy
Item
biopsy proven adenocarcinoma, superior margin of the tumour within 15cm of the anal verge on rigid sigmoidoscopy
boolean
C0001418 (UMLS CUI [1])
C0005558 (UMLS CUI [2])
C1269830 (UMLS CUI [3,1])
C1282910 (UMLS CUI [3,2])
C1317308 (UMLS CUI [3,3])
C0399626 (UMLS CUI [4])
distant metastasis | irradiation of pelvis | Inflammatory Bowel Diseases | medical condition Exclusion Radical therapy
Item
distant metastasis, prior pelvic irradiation, inflammatory bowel disease, medical conditions which preclude radical therapy
boolean
C1269798 (UMLS CUI [1])
C0747411 (UMLS CUI [2])
C0021390 (UMLS CUI [3])
C3843040 (UMLS CUI [4,1])
C2828389 (UMLS CUI [4,2])
C0260176 (UMLS CUI [4,3])
Malignant Neoplasms | Skin carcinoma | Carcinoma in situ of uterine cervix
Item
history of malignancy within five years (except nonmelanoma skin cancer, cin cervix)
boolean
C0006826 (UMLS CUI [1])
C0699893 (UMLS CUI [2])
C0851140 (UMLS CUI [3])
Pregnancy
Item
pregnancy
boolean
C0032961 (UMLS CUI [1])
Hypersensitivity celecoxib | Hypersensitivity Anti-Inflammatory Agents, Non-Steroidal | Hypersensitivity Sulfonamides | Hypersensitivity Fluorouracil
Item
hypersensitivity to celecoxib, nsaid, sulfonamides or 5-fu
boolean
C0020517 (UMLS CUI [1,1])
C0538927 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0003211 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0038760 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C0016360 (UMLS CUI [4,2])
Comorbidity Significant
Item
significant comorbid illness
boolean
C0009488 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
Peptic Ulcer | Gastrointestinal Hemorrhage NSAID Related
Item
history of peptic ulcer disease or nsaid-related gastrointestinal bleeding
boolean
C0030920 (UMLS CUI [1])
C0017181 (UMLS CUI [2,1])
C0003211 (UMLS CUI [2,2])
C0439849 (UMLS CUI [2,3])
Aspirin | Anti-Inflammatory Agents, Non-Steroidal | Cyclooxygenase 2 Inhibitors
Item
use of aspirin, other nsaid or coxib in the two weeks prior to study entry
boolean
C0004057 (UMLS CUI [1])
C0003211 (UMLS CUI [2])
C1257954 (UMLS CUI [3])
Absolute neutrophil count | Platelet Count measurement | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Creatinine measurement, serum
Item
neutrophil count <1.5x109/l, platelet count <100x109/l, serum bilirubin >1.25xuln (upper limit of normal), ast/alt >3xuln, serum creatinine >1.25xuln
boolean
C0948762 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C1278039 (UMLS CUI [3])
C0201899 (UMLS CUI [4])
C0201836 (UMLS CUI [5])
C0201976 (UMLS CUI [6])