Systolic dysfunction with ejection fraction ≤40%
Item
systolic dysfunction with ejection fraction ≤40%
boolean
C0749225 (UMLS CUI [1])
C0232174 (UMLS CUI [2])
NYHA
Item
symptomatic heart failure class 2-3
boolean
C1275491 (UMLS CUI [1])
Age
Item
>18 years of age
boolean
C0001779 (UMLS CUI [1])
optimal medical therapy of hf excluding the use of any beta-blockers
Item
optimal medical therapy of hf excluding the use of any beta-blockers within the previous 30 days of the study
boolean
C0087111 (UMLS CUI [1,1])
C0018801 (UMLS CUI [1,2])
C0001645 (UMLS CUI [2])
active myocarditis
Item
active myocarditis
boolean
C0027059 (UMLS CUI [1])
valvular heart disease
Item
hemodynamically significant valvular heart disease
boolean
C0018824 (UMLS CUI [1])
hypertrophic cardiomyopathy
Item
hypertrophic cardiomyopathy
boolean
C0007194 (UMLS CUI [1])
contraindications to beta-blockers
Item
contra-indications to beta-blockers
boolean
C1301624 (UMLS CUI [1,1])
C0001645 (UMLS CUI [1,2])
concomitant use of beta-agonists
Item
concomitant use of beta-agonists
boolean
C0001644 (UMLS CUI [1])
beta-antagonist or anti-arrhythmics
Item
beta-antagonist or anti-arrhythmics
boolean
C0001645 (UMLS CUI [1])
C0003195 (UMLS CUI [2])
Unstable angina
Item
unstable angina
boolean
C0002965 (UMLS CUI [1])
myocardial infarction or bypass surgery
Item
myocardial infarction or bypass surgery within 3 months
boolean
C0027051 (UMLS CUI [1])
C0010055 (UMLS CUI [2])
renal insufficiency, liver disease, or anemia
Item
significant renal insufficiency [creatinine >2.5 mg/dl], liver disease, or anemia
boolean
C0201976 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
C0002871 (UMLS CUI [3])