Colorectal Carcinoma
Item
histologically confirmed colorectal cancer
boolean
C0009402 (UMLS CUI [1])
Age
Item
age 18-75
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
eastern cooperative oncology group (ecog) performance status 0-1
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
life expectancy of at least 12 months
boolean
C0023671 (UMLS CUI [1])
total recovery sequelae Postoperative
Item
full recovery from any post operative sequelae
boolean
C0683340 (UMLS CUI [1,1])
C0243088 (UMLS CUI [1,2])
C0032790 (UMLS CUI [1,3])
Liver function | Serum total bilirubin measurement | Liver Function Tests
Item
adequate hepatic function as documented by a serum bilirubin < 18 umol/l, and liver function tests (lfts) within 1.5x normal range
boolean
C0232741 (UMLS CUI [1])
C1278039 (UMLS CUI [2])
C0023901 (UMLS CUI [3])
Informed consent
Item
informed consent
boolean
C0021430 (UMLS CUI [1])
Mental disorders Pre-existing | Dementia | Alcohol abuse | On psychotropic medication Causing Cognitive problems | short-acting benzodiazepines | Nausea | Sleep
Item
any major pre-existing psychiatric history or dementia, alcohol abuse, or currently using a psychotropic medication that might lead to cognitive problems, other than short acting benzodiazepines for nausea or sleep
boolean
C0004936 (UMLS CUI [1,1])
C2347662 (UMLS CUI [1,2])
C0497327 (UMLS CUI [2])
C0085762 (UMLS CUI [3])
C3874456 (UMLS CUI [4,1])
C0678227 (UMLS CUI [4,2])
C3842628 (UMLS CUI [4,3])
C0682884 (UMLS CUI [5])
C0027497 (UMLS CUI [6])
C0037313 (UMLS CUI [7])
Neoplasm Metastasis Evidence | Neoplasm Metastasis Limited | CNS involvement | Imaging of brain | Magnetic Resonance Imaging | X-Ray Computed Tomography
Item
any evidence of metastatic disease other than group c who may have limited metastatic disease. if there is clinical suspicion of central nervous system (cns) involvement patients must have brain imaging (mri or ct scan) prior to recruitment.
boolean
C0027627 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C0027627 (UMLS CUI [2,1])
C0439801 (UMLS CUI [2,2])
C0449389 (UMLS CUI [3])
C0203860 (UMLS CUI [4])
C0024485 (UMLS CUI [5])
C0040405 (UMLS CUI [6])
Sepsis Continuous | Communicable Diseases Uncontrolled | HIV Infections
Item
ongoing sepsis or uncontrolled infection, including hiv infection
boolean
C0243026 (UMLS CUI [1,1])
C0549178 (UMLS CUI [1,2])
C0009450 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0019693 (UMLS CUI [3])
nervous system disorder Pre-existing Interferes with cognitive testing
Item
pre-existing neurological condition likely to interfere with ability to perform cognitive testing
boolean
C0027765 (UMLS CUI [1,1])
C2347662 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C0204471 (UMLS CUI [1,4])
Comorbidity Severe Study Subject Participation Status Limited
Item
any other severe co-morbidity which, in the judgement of the investigator, would make the patient inappropriate for entry into this study
boolean
C0009488 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C2348568 (UMLS CUI [1,3])
C0439801 (UMLS CUI [1,4])
Malignant Neoplasms | Squamous cell carcinoma of skin | Basal cell carcinoma | Carcinoma in situ of uterine cervix | Colorectal Carcinoma
Item
active cancer within the last 5 years other than squamous or basal cell carcinoma of the skin or cervical cancer in situ (except for crc)
boolean
C0006826 (UMLS CUI [1])
C0553723 (UMLS CUI [2])
C0007117 (UMLS CUI [3])
C0851140 (UMLS CUI [4])
C0009402 (UMLS CUI [5])
Prior Chemotherapy | Chemotherapy, Adjuvant
Item
previous history of chemotherapy, other than adjuvant chemotherapy for group c metastatic group > 1 year previously
boolean
C1514457 (UMLS CUI [1])
C0085533 (UMLS CUI [2])
literacy skills English Language Minimal | Protocol Compliance | Able to read Questionnaires
Item
minimal english skills such that subjects would be unable to follow simple, written english instructions and to read questionnaires of a grade 8 standard with the help of a research assistant.
boolean
C0678998 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
C0547040 (UMLS CUI [1,3])
C0525058 (UMLS CUI [2])
C0586740 (UMLS CUI [3,1])
C0034394 (UMLS CUI [3,2])