Chronic Lymphocytic Leukemia | stage, chronic lymphocytic leukemia
Item
stage ii, iii or iv chronic lymphocytic leukemia
boolean
C0023434 (UMLS CUI [1])
C0280248 (UMLS CUI [2])
Disease Requirement Chemotherapy
Item
disease requires chemotherapeutic treatment
boolean
C0012634 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0392920 (UMLS CUI [1,3])
Tumor size Measurable | X-Ray Computed Tomography | Magnetic Resonance Imaging
Item
ct or mri scan confirming measurable tumor size
boolean
C0475440 (UMLS CUI [1,1])
C1513040 (UMLS CUI [1,2])
C0040405 (UMLS CUI [2])
C0024485 (UMLS CUI [3])
CD Antigens Documentation
Item
documentation of cd markers
boolean
C0003322 (UMLS CUI [1,1])
C0175636 (UMLS CUI [1,2])
Prior Therapy
Item
up to one prior treatment regimen
boolean
C1514463 (UMLS CUI [1])
Survival time Expected
Item
expected survival greater than 6 months
boolean
C2919552 (UMLS CUI [1,1])
C1517001 (UMLS CUI [1,2])
ECOG performance status
Item
ecog performance status of 0-2
boolean
C1520224 (UMLS CUI [1])
Renal function | Bone Marrow function | Liver function
Item
adequate renal, bone marrow and liver functions
boolean
C0232804 (UMLS CUI [1])
C0005953 (UMLS CUI [2,1])
C0031843 (UMLS CUI [2,2])
C0232741 (UMLS CUI [3])
Childbearing Potential Pregnancy test negative
Item
negative pregnancy test (females of childbearing potential)
boolean
C3831118 (UMLS CUI [1,1])
C0427780 (UMLS CUI [1,2])
Fertility Contraceptive methods
Item
must agree to use acceptable birth control, if fertile
boolean
C0015895 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Informed consent
Item
must complete informed consent
boolean
C0021430 (UMLS CUI [1])
Heart Diseases | Cardiac function
Item
no heart disease and must have adequate cardiac function
boolean
C0018799 (UMLS CUI [1])
C0232164 (UMLS CUI [2])
Hepatitis B test negative | Hepatitis C test negative
Item
must test negative for viral hepatitis b and c
boolean
C1611173 (UMLS CUI [1])
C1619717 (UMLS CUI [2])
Prior Therapy Chronic Lymphocytic Leukemia
Item
more than one prior treatment for chronic lymphocytic leukemia
boolean
C1514463 (UMLS CUI [1,1])
C0023434 (UMLS CUI [1,2])
Hypersensitivity Nipent | Hypersensitivity Rituxan | Hypersensitivity Cytoxan | Hypersensitivity Nipent Compound | Hypersensitivity Rituxan Compound | Hypersensitivity Cytoxan Compound
Item
known sensitivity to nipent, rituxan or cytoxan or any component of these drugs
boolean
C0020517 (UMLS CUI [1,1])
C0591865 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0732355 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0699319 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C0591865 (UMLS CUI [4,2])
C1706082 (UMLS CUI [4,3])
C0020517 (UMLS CUI [5,1])
C0732355 (UMLS CUI [5,2])
C1706082 (UMLS CUI [5,3])
C0020517 (UMLS CUI [6,1])
C0699319 (UMLS CUI [6,2])
C1706082 (UMLS CUI [6,3])
HIV | Acquired Immunodeficiency Syndrome
Item
known hiv or aids illness
boolean
C0019682 (UMLS CUI [1])
C0001175 (UMLS CUI [2])
Thyroid Disease Requirement Pharmaceutical Preparations
Item
thyroid disease requiring medication
boolean
C0040128 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0013227 (UMLS CUI [1,3])
Malignant Neoplasms Affecting Diagnosis | Malignant Neoplasms Affecting research results
Item
history of any malignancy that could affect the diagnosis or assessment of the study treatment
boolean
C0006826 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0011900 (UMLS CUI [1,3])
C0006826 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0683954 (UMLS CUI [2,3])
Pregnancy | Breast Feeding
Item
pregnancy or breast feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Hepatitis B Evidence | Hepatitis C Evidence
Item
evidence of hepatitis b or c infection
boolean
C0019163 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C0019196 (UMLS CUI [2,1])
C0332120 (UMLS CUI [2,2])
Protocol Compliance
Item
inability to comply with the requirements of the study
boolean
C0525058 (UMLS CUI [1])