cutaneous t-cell lymphoma
Item
persistent or recurrent cutaneous t-cell lymphoma (ctcl) stage ib-iva as defined by tnm staging.
boolean
C0079773 (UMLS CUI [1])
cytologically confirmed
Item
pathologic proven diagnosis (cytologically confirmed) of ctcl documented in patient history.
boolean
C0011900 (UMLS CUI [1,1])
C0205462 (UMLS CUI [1,2])
kidney/liver function
Item
preserved organ function: creatinine and/or liver function levels <1.5 times institutional upper limits of normal (uln).
boolean
C0232804 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
adequate liver function
Item
adequate liver function as indicated by bilirubin < or equal to 1.5 times uln, alt < or equal to 2 times uln, ast < or equal to 2 times uln.
boolean
C0201913 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
albumin
Item
albumin >3.0 g/dl
boolean
C0201838 (UMLS CUI [1])
renal function SCr
Item
adequate renal function as indicated by scr < or equal to 2.5 mg/dl.
boolean
C0201976 (UMLS CUI [1])
ecog performance status
Item
ecog performance status between 0-2.
boolean
C1520224 (UMLS CUI [1])
pregnancy test and contraceptive methods
Item
women of childbearing potential should be screened for pregnancy prior to treatment and utilize effective contraceptive methods (e.g. barrier) during treatment period.
boolean
C0032976 (UMLS CUI [1])
C0700589 (UMLS CUI [2])
age and informed consent
Item
patients over the age of 18 who are willing and able to provide informed consent.
boolean
C0001779 (UMLS CUI [1])
C0021430 (UMLS CUI [2])
peripheral t-cell lymphoma
Item
pathology consistent with peripheral t-cell lymphoma.
boolean
C0079774 (UMLS CUI [1])
stage IVB
Item
stage ivb (visceral involvement with ctcl, other than lymph node involvement).
boolean
C0854831 (UMLS CUI [1])
HIV, HBV, HCV
Item
history of human immunodeficiency virus (hiv), hepatitis b or hepatitis c infection.
boolean
C0019699 (UMLS CUI [1])
C0149709 (UMLS CUI [2])
C1112419 (UMLS CUI [3])
pregnant or breast feeding
Item
patients who are pregnant or breast feeding.
boolean
C0549206 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])
allergy to diphtheria toxin or il-2
Item
allergy to or have history of allergy to diphtheria toxin or il-2.
boolean
C0020517 (UMLS CUI [1,1])
C0661882 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0021756 (UMLS CUI [2,2])
previous ontak usage
Item
previous ontak® usage.
boolean
C2114648 (UMLS CUI [1,1])
C0722264 (UMLS CUI [1,2])
unstable cardiovascular disease
Item
unstable cardiovascular disease.
boolean
C0007222 (UMLS CUI [1])
systemic or topical antineoplastic therapy or investigational medications
Item
patients who have received systemic or topical antineoplastic therapy or investigational medications within past 14 days. exception: clear evidence of disease progression requiring immediate intervention and in the absence of ongoing toxicity from prior therapy.
boolean
C2346834 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
deep vein thrombosis
Item
ongoing deep vein thrombosis or a diagnosis of deep vein thrombosis less than 3 months prior to protocol enrollment.
boolean
C0149871 (UMLS CUI [1])