Body mass index | Body Weight
Item
have body mass index (bmi) between 18.5 kg/m2 and 35 kg/m2 and body weight no greater than 120 kg.
boolean
C1305855 (UMLS CUI [1])
C0005910 (UMLS CUI [2])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive methods | Gender Sexually active Contraceptive methods
Item
if female, must not be pregnant or lactating, and if of childbearing potential or sexually active, must use acceptable method of birth control.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0079399 (UMLS CUI [4,1])
C0241028 (UMLS CUI [4,2])
C0700589 (UMLS CUI [4,3])
Disease Clinical Significance | Coronary Artery Disease | Diabetes Mellitus | Chronic Kidney Insufficiency | Asthma
Item
have clinically significant acute or chronic disease (e.g., coronary artery disease, diabetes, chronic renal insufficiency, asthma).
boolean
C0012634 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
C1956346 (UMLS CUI [2])
C0011849 (UMLS CUI [3])
C0403447 (UMLS CUI [4])
C0004096 (UMLS CUI [5])
major surgery
Item
have major surgery within eight weeks of dosing.
boolean
C0679637 (UMLS CUI [1])
Virus Disease
Item
have overt viral illness within four weeks of dosing.
boolean
C0042769 (UMLS CUI [1])
Bleeding tendency | Bleeding tendency Family history
Item
have tendency or history in family of tendency for bleeding.
boolean
C1458140 (UMLS CUI [1])
C1458140 (UMLS CUI [2,1])
C0241889 (UMLS CUI [2,2])
Laboratory test result abnormal Clinical Significance | Chemistry abnormal | Hematology finding abnormal | Urinalysis abnormal
Item
have clinically significant abnormalities on clinical laboratory tests (chemistry, hematology, urinalysis).
boolean
C0438215 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
C0740327 (UMLS CUI [2])
C0475182 (UMLS CUI [3])
C0438142 (UMLS CUI [4])
Aspirin | Anti-Inflammatory Agents, Non-Steroidal
Item
have taken aspirin or any other non-steroidal anti-inflammatory drug (nsaid) within 10 days prior to admission to study facility.
boolean
C0004057 (UMLS CUI [1])
C0003211 (UMLS CUI [2])
medical condition | Antiplatelet Agents | clopidogrel | Ticlopidine | Dipyridamole | tirofiban | eptifibatide | abciximab | Adenosine | Epoprostenol | Anticoagulants | Vitamin K Antagonist | thrombin inhibitors | Heparin | Hirudin | argatroban | Factor Xa inhibitors
Item
have ever taken or received any of the following for medical conditions: (antiplatelet compounds including clopidogrel, ticlopidine, dipyridamole, tirofiban, eptifibatide, abciximab, adenosine, and prostacyclin) or (anticoagulants including vitamin k antagonists, thrombin inhibitors, heparins, hirudin or related compounds, argatroban and factor xa inhibitors)
boolean
C3843040 (UMLS CUI [1])
C0085826 (UMLS CUI [2])
C0070166 (UMLS CUI [3])
C0040207 (UMLS CUI [4])
C0012582 (UMLS CUI [5])
C0247025 (UMLS CUI [6])
C0253563 (UMLS CUI [7])
C0288672 (UMLS CUI [8])
C0001443 (UMLS CUI [9])
C0033567 (UMLS CUI [10])
C0003280 (UMLS CUI [11])
C2267235 (UMLS CUI [12])
C2746042 (UMLS CUI [13])
C0019134 (UMLS CUI [14])
C0019573 (UMLS CUI [15])
C0048470 (UMLS CUI [16])
C3669283 (UMLS CUI [17])
ECG abnormality Clinical Significance
Item
have a clinically significant ecg abnormality.
boolean
C1832603 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])