Breast Carcinoma | Metastatic Neoplasm persistent | Metastatic Neoplasm Recurrent
Item
patients with histologically confirmed breast cancer or other cancer which is persistent and metastatic or recurrent and metastatic.
boolean
C0678222 (UMLS CUI [1])
C2939420 (UMLS CUI [2,1])
C0205322 (UMLS CUI [2,2])
C2939420 (UMLS CUI [3,1])
C2945760 (UMLS CUI [3,2])
Therapeutic procedure Malignant Neoplasms | Therapeutic procedure Initial | Disease Free of | Skin carcinoma Treated | Carcinoma in situ of uterine cervix Treated
Item
patients with a history of treatment for other prior malignancy will be eligible, provided they remain disease-free > 2 years after initial treatment, or were treated for non-melanoma skin cancer, or in situ cervical cancer.
boolean
C0087111 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C0205265 (UMLS CUI [2,2])
C0012634 (UMLS CUI [3,1])
C0332296 (UMLS CUI [3,2])
C0699893 (UMLS CUI [4,1])
C1522326 (UMLS CUI [4,2])
C0851140 (UMLS CUI [5,1])
C1522326 (UMLS CUI [5,2])
Anatomical sites Metastatic Measurable | Diameter size
Item
patients must have at least 3 distinct measurable metastatic sites at least 1 cm of larger in their largest diameter.
boolean
C0005898 (UMLS CUI [1,1])
C0036525 (UMLS CUI [1,2])
C1513040 (UMLS CUI [1,3])
C1301886 (UMLS CUI [2,1])
C0456389 (UMLS CUI [2,2])
Age
Item
age >18 years.
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status <2 (karnofsky >50%).
boolean
C1520224 (UMLS CUI [1])
Life Expectancy
Item
life expectancy > 3 months.
boolean
C0023671 (UMLS CUI [1])
Immunotherapy
Item
patients who have had immunotherapy within 4 weeks prior to entering the study.
boolean
C0021083 (UMLS CUI [1])
Allergic Reaction GM-CSF
Item
patients who have had prior allergic reaction to gm-csf
boolean
C1527304 (UMLS CUI [1,1])
C0079460 (UMLS CUI [1,2])
Steroid therapy | Therapeutic immunosuppression
Item
patients on steroid therapy or other immunosuppressive therapy.
boolean
C0149783 (UMLS CUI [1])
C0021079 (UMLS CUI [2])
Investigational New Drugs
Item
patients undergoing therapy with other investigational agents.
boolean
C0013230 (UMLS CUI [1])
Metastatic malignant neoplasm to brain | Lesion of brain | Target Lesion Identification | Non-Target Lesion Identification
Item
patients with known brain metastases can be included in this clinical trial but brain lesions are not eligible as target or non target lesion.
boolean
C0220650 (UMLS CUI [1])
C0221505 (UMLS CUI [2])
C2986546 (UMLS CUI [3])
C2986547 (UMLS CUI [4])
Comorbidity Uncontrolled | Communicable Diseases | Symptomatic congestive heart failure | Myocardial Infarction | Angina, Unstable | Cardiac Arrhythmia Unstable
Item
uncontrolled inter-current illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, myocardial infarction within the past 6 months, unstable angina pectoris, or unstable cardiac arrhythmia requiring assessment for clinical intervention.
boolean
C0009488 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0009450 (UMLS CUI [2])
C0742758 (UMLS CUI [3])
C0027051 (UMLS CUI [4])
C0002965 (UMLS CUI [5])
C0003811 (UMLS CUI [6,1])
C0443343 (UMLS CUI [6,2])