Gender | Age
Item
women >=18 years;
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Locally advanced breast cancer | Carcinoma breast stage IV
Item
locally advanced or metastatic breast cancer;
boolean
C3495949 (UMLS CUI [1])
C0278488 (UMLS CUI [2])
HER2-positive carcinoma of breast | Fluorescent in situ hybridisation positive | Immunohistochemistry Score
Item
her-2 overexpression (fish + or ihc 3+);
boolean
C1960398 (UMLS CUI [1])
C3495875 (UMLS CUI [2])
C0021044 (UMLS CUI [3,1])
C0449820 (UMLS CUI [3,2])
Measurable lesion Quantity
Item
>=1 measurable lesion;
boolean
C1513041 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
Anthracycline | Metastatic Neoplasm
Item
up to one prior anthracycline-based chemotherapy regimen in a metastatic setting.
boolean
C0003234 (UMLS CUI [1])
C2939420 (UMLS CUI [2])
Neuropathy Pre-existing
Item
pre-existing neuropathy >=grade 2;
boolean
C0442874 (UMLS CUI [1,1])
C2347662 (UMLS CUI [1,2])
CNS metastases
Item
known cns metastases;
boolean
C0686377 (UMLS CUI [1])
Congestive heart failure | Myocardial Infarction
Item
congestive heart failure, or myocardial infarction within the last 6 months;
boolean
C0018802 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
Malignant Neoplasms | Basal cell carcinoma Cured | Carcinoma in situ of uterine cervix Cured
Item
previous malignancies in last 5 years, except for cured basal cell cancer of the skin, or cancer in situ of the cervix.
boolean
C0006826 (UMLS CUI [1])
C0007117 (UMLS CUI [2,1])
C1880198 (UMLS CUI [2,2])
C0851140 (UMLS CUI [3,1])
C1880198 (UMLS CUI [3,2])