Age
Item
1. subjects must be at least 18 years old at the time of study screening
boolean
C0001779 (UMLS CUI [1])
Schizophrenia
Item
2. subjects must have a diagnosis of schizophrenia as defined by dsm-v129 criteria and confirmed by the structured clinical interview for dsm-iv (scid-p).
boolean
C0036341 (UMLS CUI [1])
Decision Capability | Study Subject Participation Status
Item
3. subjects must demonstrate adequate decisional capacity, in the judgment of the consenting study staff member, to make a choice about participating in this research study.
boolean
C0679006 (UMLS CUI [1,1])
C2698977 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2])
Stable status Clinical
Item
4. subjects must have been clinically stable (non-acute) for 8 weeks prior to consent; in the judgment of the site principal investigator.
boolean
C0205360 (UMLS CUI [1,1])
C0205210 (UMLS CUI [1,2])
Antipsychotic Agents Therapeutic procedure Stable status | Therapeutic procedure Psychotropic Drugs concomitant
Item
5. subjects must have been maintained on a stable treatment of antipsychotics and/or other concomitant psychotropic treatment for at least 6 weeks prior to consent.
boolean
C0040615 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0087111 (UMLS CUI [2,1])
C0033978 (UMLS CUI [2,2])
C0521115 (UMLS CUI [2,3])
Learned English Language | Age | Neuropsychology Validity of Results
Item
6. subjects must have learned english before the age of 12 to ensure valid neuropsychological results
boolean
C0023185 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
C0001779 (UMLS CUI [2])
C0027903 (UMLS CUI [3,1])
C0042284 (UMLS CUI [3,2])
Capacity Visual | Capacity Auditory | motor ability | Intervention regimes Computer Systems
Item
7. subjects must have the visual, auditory, and motor capacity to use the computerized intervention in the judgment of the consenting study staff person.
boolean
C1516240 (UMLS CUI [1,1])
C0234621 (UMLS CUI [1,2])
C1516240 (UMLS CUI [2,1])
C0439825 (UMLS CUI [2,2])
C0260026 (UMLS CUI [3])
C1273869 (UMLS CUI [4,1])
C0009612 (UMLS CUI [4,2])
Hallucinations Moderate | Unusual Thought Content Moderate | Positive and negative syndrome scale
Item
8. subjects must have no more than a moderate severity rating on hallucinations and unusual thought content as shown by a score of ≤ 4 on the positive and negative symptoms scale (panss).
boolean
C0018524 (UMLS CUI [1,1])
C0205081 (UMLS CUI [1,2])
C3639370 (UMLS CUI [2,1])
C0205081 (UMLS CUI [2,2])
C0451383 (UMLS CUI [3])
psychiatric hospitalization
Item
1. subjects should not have had a psychiatric hospitalization in the 8 weeks prior to consent.
boolean
C0748061 (UMLS CUI [1])
Intoxication | controlled substance Influence
Item
2. subjects who appear to be intoxicated or under the influence of a controlled substance on any day of assessment must be rescheduled or discontinued based upon the discretion of the site staff evaluator.
boolean
C0728899 (UMLS CUI [1])
C0678485 (UMLS CUI [2,1])
C4054723 (UMLS CUI [2,2])
Mental Retardation | Intelligence quotient | Pervasive Development Disorder | nervous system disorder | Traumatic Brain Injury | Epilepsy | Parkinson Disease
Item
3. subjects should not have a history of mental retardation (iq<70 based on wtar132) or pervasive developmental disorder; or other neurological disorder (e.g., traumatic brain injury, epilepsy, parkinson's disease.)
boolean
C0025362 (UMLS CUI [1])
C0456149 (UMLS CUI [2])
C0524528 (UMLS CUI [3])
C0027765 (UMLS CUI [4])
C0876926 (UMLS CUI [5])
C0014544 (UMLS CUI [6])
C0030567 (UMLS CUI [7])
Computer-Assisted Cognitive Training
Item
4. subjects should not have been treated within 5 years of the date of consent with a computer-based cognitive training program manufactured by posit science.
boolean
C3899511 (UMLS CUI [1])
Study Subject Participation Status | Clinical Trial Affecting research results
Item
5. subjects should not be participating in a concurrent clinical trial that, in the judgment of the site principal investigator, could affect the outcome of this one.
boolean
C2348568 (UMLS CUI [1])
C0008976 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0683954 (UMLS CUI [2,3])
Antipsychotic Agents Quantity | adjunctive treatment Pharmaceutical Preparations Anticholinergic adverse reaction
Item
6. subjects should not be prescribed more than two anti-psychotics. subjects should not be routinely treated with adjunctive medication with known significant anticholinergic side effects including diphenhydramine and/or benztropine.
boolean
C0040615 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C3858690 (UMLS CUI [2,1])
C0013227 (UMLS CUI [2,2])
C0569703 (UMLS CUI [2,3])
Feeling suicidal | Columbia suicide severity rating scale | Suicidal behavior | Actual Suicide Attempt | Interrupted Suicide Attempt | Aborted Suicide Attempt | Preparatory actions toward imminent suicidal behavior
Item
7. subjects who have answered 'yes' to question 5 (active suicidal ideation with specific plan and intent) on the columbia-suicide severity rating scale, c-ssrs, or who have answered 'yes' to any of the suicide-related behaviors (actual attempt, interrupted attempt, aborted attempt, preparatory act or behavior) on the c-ssrs "suicidal behavior" portion shall be excluded from the study if ideation or behavior occurred within one month of consent. subjects excluded for this reason will be referred for appropriate treatment.
boolean
C0424000 (UMLS CUI [1])
C3888485 (UMLS CUI [2])
C1760428 (UMLS CUI [3])
C3639923 (UMLS CUI [4])
C3639927 (UMLS CUI [5])
C3639930 (UMLS CUI [6])
C3267153 (UMLS CUI [7])