ID.1
Item
diagnosis of acute lymphoblastic leukemia
boolean
C0011900 (UMLS CUI [1,1])
C0023449 (UMLS CUI [1,2])
ID.2
Item
received prior front-line therapy on a pediatric oncology group (pog),children's cancer group (ccg), or central oncology group (cog) study
boolean
C1514463 (UMLS CUI [1,1])
C1518932 (UMLS CUI [1,2])
ID.3
Item
received induction therapy comprising vincristine, asparaginase, prednisone/dexamethasone, and daunorubicin as in ccg, pog, or cog protocols
boolean
C3179010 (UMLS CUI [1,1])
C0042679 (UMLS CUI [1,2])
C3179010 (UMLS CUI [2,1])
C0003993 (UMLS CUI [2,2])
C3179010 (UMLS CUI [3,1])
C0011777 (UMLS CUI [3,2])
C3179010 (UMLS CUI [4,1])
C3179010 (UMLS CUI [4,2])
C3179010 (UMLS CUI [5,1])
C0011015 (UMLS CUI [5,2])
ID.4
Item
m1 or m2 bone marrow status after front-line induction therapy and presenting with at least 1of the following:
boolean
C0678852 (UMLS CUI [1,1])
C0005953 (UMLS CUI [1,2])
ID.5
Item
philadelphia chromosome positive (ph+) with t(9;22)(q34;q11) by cytogenetics or fluorescence in situ hybridization
boolean
C0856536 (UMLS CUI [1])
ID.6
Item
bcr-abl fusion transcript by reverse transcription polymerase chain reaction
boolean
C1835417 (UMLS CUI [1])
ID.7
Item
hypodiploid with less than 44 chromosomes and/or dna index less than0.81
boolean
C1835417 (UMLS CUI [1])
C2919020 (UMLS CUI [2])
ID.8
Item
mll translocation (11q23) by cytogenetics and a slow early response (ser) to induction therapy, defined as at least 5% blasts at day 15 of induction and/or at least .1% minimal residual disease (mrd) after induction therapy
boolean
C0796367 (UMLS CUI [1,1])
C0796367 (UMLS CUI [1,2])
ID.9
Item
failed to achieve remission after front-line induction therapy
boolean
C0687702 (UMLS CUI [1])
ID.10
Item
m3 bone marrow status (greater than 25% blasts) after induction therapy
boolean
C0678852 (UMLS CUI [1,1])
C0005953 (UMLS CUI [1,2])
ID.11
Item
m2 bone marrow status (5-25% blasts) or at least 1% mrd after induction therapy and m2 or m3or at least 1% mrd after consolidation therapy (ccg studies) or extended induction therapy (pog or cog studies)
boolean
C0678852 (UMLS CUI [1,1])
C0005953 (UMLS CUI [1,2])
ID.12
Item
see disease characteristics
boolean
ID.13
Item
not pregnant or nursing
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])
ID.14
Item
negative pregnancy test
boolean
C0032976 (UMLS CUI [1])
ID.15
Item
fertile patients must use effective contraception
boolean
C0700589 (UMLS CUI [1])
ID.16
Item
see disease characteristics
boolean
ID.17
Item
see disease characteristics
boolean
ID.18
Item
no concurrent prophylactic cranial radiotherapy
boolean
C1522449 (UMLS CUI [1,1])
C3163632 (UMLS CUI [1,2])