Age
Item
men and women 18 years of age or older
boolean
C0001779 (UMLS CUI [1])
Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis, Primary Progressive
Item
definite relapsing remitting, secondary progressive, or primary progressive ms by revised mcdonald criteria;
boolean
C0751967 (UMLS CUI [1])
C0751965 (UMLS CUI [2])
C0751964 (UMLS CUI [3])
Kurtzke multiple sclerosis rating scale
Item
expanded disability severity scale ≤ 8 at baseline;
boolean
C0451246 (UMLS CUI [1])
Multiple Sclerosis | Biological Response Modifier Therapy | Anti-Anxiety Agents | Antidepressive Agents | Stable status
Item
stable on ms disease modifying, anxiolytic, or antidepressant medications for three months prior to baseline visit;
boolean
C0026769 (UMLS CUI [1])
C0005527 (UMLS CUI [2])
C0040616 (UMLS CUI [3])
C0003289 (UMLS CUI [4])
C0205360 (UMLS CUI [5])
stress severity rating mild | stress severity rating moderate | Perceived stress scale
Item
mild to moderate stress defined by a score of ≥ 10 on the perceived stress scale at screening;
boolean
C2020721 (UMLS CUI [1])
C2020723 (UMLS CUI [2])
C0582653 (UMLS CUI [3])
English Language Able to read Able to write
Item
ability to read and write in english;
boolean
C0376245 (UMLS CUI [1,1])
C0586740 (UMLS CUI [1,2])
C0584993 (UMLS CUI [1,3])
Informed Consent | Compliance behavior Study Protocol | stress reduction techniques
Item
willingness to provide informed consent and comply with study activities, including weekly mbsr sessions and daily practice or weekly education control classes.
boolean
C0021430 (UMLS CUI [1])
C1321605 (UMLS CUI [2,1])
C2348563 (UMLS CUI [2,2])
C0884454 (UMLS CUI [3])
stress reduction techniques | Cognitive Therapy
Item
mbsr or cognitive behavioral therapy training within the last 5 years;
boolean
C0884454 (UMLS CUI [1])
C0009244 (UMLS CUI [2])
Participation in meditation Regular | Participation in yoga Regular
Item
current regular meditation or yoga practice (weekly or more often);
boolean
C1821915 (UMLS CUI [1,1])
C0205272 (UMLS CUI [1,2])
C0454430 (UMLS CUI [2,1])
C0205272 (UMLS CUI [2,2])
Exacerbation of multiple sclerosis
Item
ms exacerbation within 30 days of baseline visit;
boolean
C0581392 (UMLS CUI [1])
Mini-mental state examination
Item
mini-mental status examination (mmse) score of ≤ 26 at screening visit;
boolean
C0451306 (UMLS CUI [1])
Feeling suicidal
Item
active suicidal ideation (beck depression inventory) at screening visit;
boolean
C0424000 (UMLS CUI [1])
psychological disease | Depressive disorder | Anxiety
Item
reported or medically recorded diagnoses of current serious psychological disorders other than depression and anxiety;
boolean
C1658764 (UMLS CUI [1])
C0011581 (UMLS CUI [2])
C0003467 (UMLS CUI [3])
Disease is life-threatening if untreated | Physical illness Severely disabling
Item
other current life-threatening or severely disabling physical disorders;
boolean
C3553594 (UMLS CUI [1])
C0683323 (UMLS CUI [2,1])
C4035398 (UMLS CUI [2,2])
Urine pregnancy test positive | Pregnancy, Planned
Item
positive pregnancy urine test at baseline and women planning pregnancy during the study period (contraception not required);
boolean
C0430059 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
Malignant Neoplasms | Basal cell carcinoma | Squamous cell carcinoma of skin
Item
cancer, other than basal or squamous skin cancers; or
boolean
C0006826 (UMLS CUI [1])
C0007117 (UMLS CUI [2])
C0553723 (UMLS CUI [3])
Informed Consent Unable
Item
inability or unwillingness of individual or legal guardian/representative to give written informed consent.
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])