Acute lymphocytic leukemia de novo | T-Cell Lymphoma de novo | B-Cell Lymphoma de novo
Item
new diagnosis of de novo all or lymphomas (t or b cell)
boolean
C0023449 (UMLS CUI [1,1])
C1515568 (UMLS CUI [1,2])
C0079772 (UMLS CUI [2,1])
C1515568 (UMLS CUI [2,2])
C0079731 (UMLS CUI [3,1])
C1515568 (UMLS CUI [3,2])
Induction Chemotherapy Planned | Adrenal Cortex Hormones | Vincristine | pegaspargase | Daunorubicin | Children's Oncology Group | Acute lymphocytic leukemia
Item
planned induction chemotherapy with a corticosteroid, vincristine and peg l-asparaginase, with or without daunorubicin consistent with the children's oncology group (cog) all trials
boolean
C3179010 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
C0001617 (UMLS CUI [2])
C0042679 (UMLS CUI [3])
C0071568 (UMLS CUI [4])
C0011015 (UMLS CUI [5])
C1516477 (UMLS CUI [6])
C0023449 (UMLS CUI [7])
Central venous catheter, device functioning
Item
functioning central venous access device
boolean
C1145640 (UMLS CUI [1,1])
C0542341 (UMLS CUI [1,2])
oral medication Able to swallow | Administration Nasogastric tube | Administration Gastric Tube
Item
must be able to tolerate oral medication or have it administered via an nasogastric tube (ngt) or gt tube
boolean
C0175795 (UMLS CUI [1,1])
C2712086 (UMLS CUI [1,2])
C0013153 (UMLS CUI [2,1])
C0085678 (UMLS CUI [2,2])
C0013153 (UMLS CUI [3,1])
C1546658 (UMLS CUI [3,2])
Age
Item
males and females,age 1 year(365 days) to < 18 (17 years and 364 days) years.
boolean
C0001779 (UMLS CUI [1])
Platelet Count measurement
Item
platelet counts ≥ 20000/microl
boolean
C0032181 (UMLS CUI [1])
leukemia CNS3
Item
central nervous system (cns) 3 status leukemia
boolean
C0023418 (UMLS CUI [1,1])
C3899748 (UMLS CUI [1,2])
Deep Vein Thrombosis | Pulmonary Embolism
Item
prior history of documented dvt or pe in the past 3 months
boolean
C0149871 (UMLS CUI [1])
C0034065 (UMLS CUI [2])
Blood Coagulation Disorder Hereditary | hereditary coagulopathy
Item
known inherited bleeding disorder or coagulopathy
boolean
C0005779 (UMLS CUI [1,1])
C0439660 (UMLS CUI [1,2])
C0679428 (UMLS CUI [2])
major surgery | Insertion of Central Venous Access Device | Bone marrow aspiration procedure | Biopsy | Hemorrhage Risk
Item
major surgery (excluding cvad placement and bone marrow aspiration and biopsy) within the last 30 days that may be associated with a risk of bleeding
boolean
C0679637 (UMLS CUI [1])
C1610121 (UMLS CUI [2])
C0398523 (UMLS CUI [3])
C0005558 (UMLS CUI [4])
C0019080 (UMLS CUI [5,1])
C0035647 (UMLS CUI [5,2])
Hypertension, severe Uncontrolled | Systolic Pressure | Diastolic blood pressure
Item
uncontrolled severe hypertension at enrollment. severe hypertension is defined as a systolic or diastolic blood pressure (bp) > 5 mm hg above the 95th percentile as defined by the national high blood pressure education program working group (nhbpep) established guidelines for the definition of normal and elevated blood pressure in children
boolean
C4013784 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0871470 (UMLS CUI [2])
C0428883 (UMLS CUI [3])
Hyperleukocytic syndrome Extreme | White Blood Cell Count procedure
Item
extreme hyperleukocytosis, white blood cell (wbc) counts over 200 x 109/l (200,000/microl) at the time of diagnosis
boolean
C3805210 (UMLS CUI [1,1])
C0205403 (UMLS CUI [1,2])
C0023508 (UMLS CUI [2])
Liver Dysfunction | Alanine aminotransferase measurement | Aspartate aminotransferase measurement | Bilirubin, direct measurement
Item
liver dysfunction manifested by sgtp (alt) > 5x upper limit of normal (uln) and/or aspartate aminotransferase (ast) >5 x uln and/or direct (conjugated) bilirubin > 2x uln
boolean
C0086565 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
C0201899 (UMLS CUI [3])
C0201916 (UMLS CUI [4])
Renal function | Age | Body Height | Creatinine-based formula (Schwartz)
Item
renal function < 30% of normal for age and size as determined by the schwartz formula
boolean
C0232804 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0005890 (UMLS CUI [3])
C1980037 (UMLS CUI [4])
Prothrombin time test | Partial thromboplastin time finding | Age | International Normalized Ratio
Item
prothrombin time(pt)> 1 second above the upper limit of normal for age,partial thromboplastin time (ptt) > 3 seconds above the upper limit of normal for age and international normalized ratio(inr) above the upper limit of normal for age, within 1 week prior to enrollment.
boolean
C0491338 (UMLS CUI [1])
C1531697 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
C0525032 (UMLS CUI [4])
Hypersensitivity apixaban | Hypersensitivity Factor Xa Inhibitors
Item
history of allergy to apixaban or factor xa inhibitors
boolean
C0020517 (UMLS CUI [1,1])
C1831808 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C2267054 (UMLS CUI [2,2])
IAdverse reaction Due to Hemorrhage Major | Adverse reaction Anticoagulants | Adverse reaction Antiplatelet Agents
Item
history of significant adverse reaction or major bleeding related adverse reaction to other anticoagulant or antiplatelet agents
boolean
C0559546 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0019080 (UMLS CUI [1,3])
C0205164 (UMLS CUI [1,4])
C0559546 (UMLS CUI [2,1])
C0003280 (UMLS CUI [2,2])
C0559546 (UMLS CUI [3,1])
C0085826 (UMLS CUI [3,2])
Drug Allergy | anaphylaxis | Hepatotoxicity
Item
history of any significant drug allergy (such as anaphylaxis or hepatotoxicity
boolean
C0013182 (UMLS CUI [1])
C0002792 (UMLS CUI [2])
C0235378 (UMLS CUI [3])