Hodgkin Disease CD30 positive | Ki-1+ Anaplastic Large Cell Lymphoma | Allogeneic Stem Cell Transplantation | Match Living related donor | Match Living unrelated donor
Item
1. patients with cd30 positive hodgkin lymphoma (hl) or anaplastic large cell lymphoma (alcl) that have undergone allogeneic sct in the past 60 days (matched related or matched unrelated donors only).
boolean
C0019829 (UMLS CUI [1,1])
C3888910 (UMLS CUI [1,2])
C0206180 (UMLS CUI [2])
C2242529 (UMLS CUI [3])
C1708943 (UMLS CUI [4,1])
C3494891 (UMLS CUI [4,2])
C1708943 (UMLS CUI [5,1])
C3494890 (UMLS CUI [5,2])
Age
Item
2. age 18 to 65 years.
boolean
C0001779 (UMLS CUI [1])
Zubrod Performance Status Karnofsky Performance Status
Item
3. performance status: zubrod 0-1 or karnofsky 80-100.
boolean
C3714786 (UMLS CUI [1,1])
C0206065 (UMLS CUI [1,2])
Creatinine measurement, serum | Creatinine clearance measurement Creatinine-based formula (MDRD)
Item
4. serum creatinine < 1.5 mg/dl or creatinine clearance greater than or equal to 40 cc/min as defined by mdrd method from national kidney disease education program (nkdep).
boolean
C0201976 (UMLS CUI [1])
C0373595 (UMLS CUI [2,1])
C1980036 (UMLS CUI [2,2])
Serum bilirubin direct | Gilbert Disease
Item
5. serum direct bilirubin < 1.5 mg/dl (unless gilbert's syndrome).
boolean
C0858048 (UMLS CUI [1])
C0017551 (UMLS CUI [2])
SGPT - Glutamate pyruvate transaminase | Malignant Neoplasms
Item
6. serum glutamate pyruvate transaminase (sgpt) < 200 iu/l unless related to patient's malignancy.
boolean
C0376147 (UMLS CUI [1])
C0006826 (UMLS CUI [2])
Neutrophil Engraftment | Platelet Engraftment | Platelet Count measurement | Platelet Transfusion | Absolute neutrophil count | Growth Factor
Item
7. evidence of neutrophil and platelet engraftment, defined as platelet count equal or greater than 50,000 mm3 independent of platelet transfusion and absolute neutrophil count (anc) equal or greater to 1000 without growth factor support for at least 5 days.
boolean
C1882078 (UMLS CUI [1])
C1882407 (UMLS CUI [2])
C0032181 (UMLS CUI [3])
C0086818 (UMLS CUI [4])
C0948762 (UMLS CUI [5])
C0018284 (UMLS CUI [6])
BRENTUXIMAB Exposure Previous
Item
8. patients with previous exposure to brentuximab pre-transplant are eligible for the study.
boolean
C3247294 (UMLS CUI [1,1])
C0332157 (UMLS CUI [1,2])
C0205156 (UMLS CUI [1,3])
Pregnancy | Breast Feeding | Childbearing Potential | Menarche Female Sterilization | Postmenopausal state Serum pregnancy test positive
Item
1. pregnancy or breast-feeding (women of childbearing potential, any female who has experienced menarche and who has not undergone surgical sterilization or is post-menopausal with a positive serum pregnancy test.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3])
C0025274 (UMLS CUI [4,1])
C0015787 (UMLS CUI [4,2])
C0232970 (UMLS CUI [5,1])
C0430063 (UMLS CUI [5,2])
Acute GVH disease | Steroids Unresponsive to Treatment
Item
2. presence of steroid-refractory acute graft-versus-host disease (gvhd).
boolean
C0856825 (UMLS CUI [1])
C0038317 (UMLS CUI [2,1])
C0205269 (UMLS CUI [2,2])
Transplantation, Homologous | Therapeutic procedure Graft failure
Item
3. patients that underwent allogeneic transplantation as a treatment of graft failure.
boolean
C0040739 (UMLS CUI [1])
C0087111 (UMLS CUI [2,1])
C1262018 (UMLS CUI [2,2])
Cytomegalovirus infection reactivation Unresponsive to Treatment Double Foscarnet | Cytomegalovirus infection reactivation Unresponsive to Treatment Double Ganciclovir | Cytomegalovirus Infections
Item
4. dual refractory cmv reactivation to foscarnet and ganciclovir or evidence of cmv disease.
boolean
C1142560 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
C0205173 (UMLS CUI [1,3])
C0070895 (UMLS CUI [1,4])
C1142560 (UMLS CUI [2,1])
C0205269 (UMLS CUI [2,2])
C0205173 (UMLS CUI [2,3])
C0017066 (UMLS CUI [2,4])
C0010823 (UMLS CUI [3])