Age
Item
18 years and older
boolean
C0001779 (UMLS CUI [1])
Heart failure | Left ventricular ejection fraction | Diastolic left ventricular internal diameter End diastole | Body Surface Area | Echocardiography
Item
history of heart failure with an lvef (less than or equal to) < 0.35 for at least 6 months or an lvef < 0.45 with left ventricular internal end diastole (defined by a diameter of more than 2.9 cm per square meter of body surface area or more than 6.5 cm on the basis of echocardiography).
boolean
C0018801 (UMLS CUI [1])
C0428772 (UMLS CUI [2])
C0919652 (UMLS CUI [3,1])
C1562146 (UMLS CUI [3,2])
C0005902 (UMLS CUI [4])
C0013516 (UMLS CUI [5])
New York Heart Association Classification
Item
new york heart association (nyha) class ii-iv
boolean
C1275491 (UMLS CUI [1])
Therapeutic procedure Background Heart failure | Angiotensin-Converting Enzyme Inhibitors | Angiotensin II receptor antagonist | Adrenergic beta-Antagonists | intolerance to Angiotensin-Converting Enzyme Inhibitors | intolerance to Angiotensin II receptor antagonist | intolerance to Adrenergic beta-Antagonists ,
Item
background heart failure therapy that includes angiotensin converting enzyme inhibitors (acei) or angiotensin receptor blockers (arbs), and beta blockers (bbs) for at least 3 months (or documentation of intolerance to acei/arbs and bbs)
boolean
C0087111 (UMLS CUI [1,1])
C1706907 (UMLS CUI [1,2])
C0018801 (UMLS CUI [1,3])
C0003015 (UMLS CUI [2])
C0521942 (UMLS CUI [3])
C0001645 (UMLS CUI [4])
C1744706 (UMLS CUI [5,1])
C0003015 (UMLS CUI [5,2])
C1744706 (UMLS CUI [6,1])
C0521942 (UMLS CUI [6,2])
C1744706 (UMLS CUI [7,1])
C0001645 (UMLS CUI [7,2])
intolerance to Nitrates | intolerance to Hydralazine
Item
no history of intolerance to either nitrates or hydralazine
boolean
C1744706 (UMLS CUI [1,1])
C0028125 (UMLS CUI [1,2])
C1744706 (UMLS CUI [2,1])
C0020223 (UMLS CUI [2,2])
Combination Drug Therapy Hydralazine Nitrates
Item
no treatment with the combination of hydralazine and nitrates for the previous 3 months
boolean
C0013218 (UMLS CUI [1,1])
C0020223 (UMLS CUI [1,2])
C0028125 (UMLS CUI [1,3])
Revascularization | Myocardial Infarction
Item
no revascularization or myocardial infarction within last 90 days
boolean
C0581603 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
Cardiac Resynchronization Therapy | Left ventricular ejection fraction
Item
can not be enrolled for at least 90 days after receiving cardiac resynchronization therapy (crt) and must have an lvef (less than or equal to) < 0.35 at least 3 months after crt.
boolean
C1167956 (UMLS CUI [1])
C0428772 (UMLS CUI [2])
Heart valve disease | Hypertrophic Cardiomyopathy | Restrictive cardiomyopathy | myocarditis; active | Uncontrolled hypertension
Item
presence of clinically significant valvular heart disease, hypertrophic or restrictive cardiomyopathy, active myocarditis, or uncontrolled hypertension.
boolean
C0018824 (UMLS CUI [1])
C0007194 (UMLS CUI [2])
C0007196 (UMLS CUI [3])
C0238294 (UMLS CUI [4])
C1868885 (UMLS CUI [5])
Pregnancy | Pregnancy, Planned | Pregnancy Preventing Unwilling
Item
women who are currently pregnant, planning on becoming pregnant in the next two years, or those who do not agree to prevent pregnancy.
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
C0032961 (UMLS CUI [3,1])
C1292733 (UMLS CUI [3,2])
C0558080 (UMLS CUI [3,3])