age; informed consent
Item
subjects aged over 70 years who have signed informed consent for participation to the study and are affiliated to a social security regimen.
boolean
C0001779 (UMLS CUI [1])
C0021430 (UMLS CUI [2])
dsm-iv; nincds/adrda criteria; mmse score
Item
for patients: subjects with probable ad according to the dsm-iv criteria and the nincds/adrda criteria and with mild to moderate probable ad: mmse score> 15.
boolean
C0220952 (UMLS CUI [1])
C2828081 (UMLS CUI [2])
C2225229 (UMLS CUI [3])
cognitive deficits; mmse score
Item
for controls: subjects without cognitive deficits on neuropsychological tests: scores of mmse > 26 and of the 5 word test equal to 10/10 and of the clock drawing test equal to 7/7.
boolean
C0009241 (UMLS CUI [1])
C2225229 (UMLS CUI [2])
guardianship
Item
guardianship
boolean
C0870627 (UMLS CUI [1])
cerebrovascular disease; parkinsons disease; dementia; epilepsy
Item
history of cerebrovascular disease, parkinson's disease, other known dementia, epilepsy
boolean
C0007820 (UMLS CUI [1])
C0030567 (UMLS CUI [2])
C0497327 (UMLS CUI [3])
C0014544 (UMLS CUI [4])
major depression
Item
major depression
boolean
C1269683 (UMLS CUI [1])
sensory disorders; deficits in language
Item
serious sensory disorders; deficits in language & comprehension
boolean
C0152027 (UMLS CUI [1])
C1866856 (UMLS CUI [2])
heart insufficiency; hepatic insufficiency; renal failure; respiratory failures
Item
serious heart or hepatic insufficiencies, renal or respiratory failures
boolean
C0018801 (UMLS CUI [1])
C1306571 (UMLS CUI [2])
C0035078 (UMLS CUI [3])
C0852895 (UMLS CUI [4])
diabetes; endocrine disorders; thyroid dysfunction; cancer; inflammatory syndrome; malnutrition
Item
unstable diabetes or endocrine disorders, thyroid dysfunction, cancer, inflammatory syndrome, malnutrition
boolean
C0011847 (UMLS CUI [1])
C0014130 (UMLS CUI [2])
C0348024 (UMLS CUI [3])
C0006826 (UMLS CUI [4])
C0242966 (UMLS CUI [5])
C0162429 (UMLS CUI [6])
cognitive training
Item
cognitive training during the 6 previous months
boolean
C1868940 (UMLS CUI [1])
steroids; anti-depressants; cholinesterase inhibitors; thyroid hormones
Item
medications: steroids (hrt, androgens, corticoids), anti-depressants, cholinesterase inhibitors, thyroid hormones, synthetic anti-thyroids
boolean
C0038317 (UMLS CUI [1])
C0003290 (UMLS CUI [2])
C0008425 (UMLS CUI [3])
C0040135 (UMLS CUI [4])
contraindication mri; claustrophobia
Item
contraindications for mri: metallic implants & claustrophobia
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0008909 (UMLS CUI [2])