Adenocarcinoma of colon
Item
histologically or cytologically proven adenocarcinoma of the colon or rectum
boolean
C0338106 (UMLS CUI [1])
metastatic disease
Item
documented progressive metastatic disease
boolean
C0027627 (UMLS CUI [1])
measurable lesion
Item
patients who have at least one uni-dimensional measurable lesion by ct-scan or mri according to response evaluation criteria in solid tumours (recist)
boolean
C1513041 (UMLS CUI [1])
performance status
Item
who performance status of 0 or 1
boolean
C1520224 (UMLS CUI [1])
laboratory values
Item
adequate laboratory values of haematology, liverfunction and renal function
boolean
C1254595 (UMLS CUI [1])
chemotherapy
Item
no previous chemotherapy for metastatic colorectal cancer
boolean
C0392920 (UMLS CUI [1])
history of neoplasm
Item
past or concurrent history of neoplasm other than colorectal adenocarcinoma, except curatively treated cancer free of disease for more than 10 years.
boolean
C0260455 (UMLS CUI [1])
bowel obstruction
Item
bowel obstruction or sub-obstruction. crohn's disease, or ulcerative colitis.
boolean
C0021843 (UMLS CUI [1])
C0010346 (UMLS CUI [2])
C0009324 (UMLS CUI [3])
medical condition
Item
other severe illness or medical condition such as unstable cardiac disease under treatment, myocardial infarction within 6 months before inclusion.
boolean
C0012634 (UMLS CUI [1])
uncontrolled infection
Item
active uncontrolled infection
boolean
C0009488 (UMLS CUI [1])
anticancer agent
Item
other concomitant anticancer agent
boolean
C0003392 (UMLS CUI [1])