solid tumor or lymphoma
Item
histologically or cytologically confirmed diagnosis of advanced and/or metastatic solid tumor or lymphoma that is refractory to standard therapy
boolean
C0280100 (UMLS CUI [1])
C0024299 (UMLS CUI [2])
measurable or evaluable disease
Item
measurable or evaluable disease
boolean
C1513041 (UMLS CUI [1])
ecog
Item
score of 0 to 2 on the ecog performance scale
boolean
C1520224 (UMLS CUI [1])
medical illness
Item
concurrent serious medical illness
boolean
C0262926 (UMLS CUI [1])
central nervous system (cns) tumor involvement
Item
known, clinically suspected, or history of central nervous system (cns) tumor involvement
boolean
C0085136 (UMLS CUI [1])
active diarrhea
Item
active diarrhea
boolean
C0011991 (UMLS CUI [1])
coagulation disorder
Item
known history of coagulation disorder
boolean
C0005779 (UMLS CUI [1])
cytochrome p450 3a4
Item
patients requiring cytochrome p450 3a4 (cyp3a4) enzyme inducing medications
boolean
C3830625 (UMLS CUI [1])
ketoconazole
Item
requirement for ketoconazole or other strong inhibitor of cyp3a4 enzymes
boolean
C0022625 (UMLS CUI [1])
chemotherapy, immunotherapy
Item
prior chemotherapy, immunotherapy, investigational agent, or other therapy used to treat the cancer within 4 weeks (6 weeks for prior treatment with mitomycin c or nitrosoureas) prior to the scheduled administration of ezn-2208
boolean
C0392920 (UMLS CUI [1])
C0021083 (UMLS CUI [2])