clozapine
Item
subjects treated with clozapine for the indication of poor response to other antipsychotic medications.
boolean
C0009079 (UMLS CUI [1])
treatment with clozapine stable dose
Item
treatment with clozapine is at a stable dose for at least 12 weeks. dose must be 400 mg/day or more, unless side effects limited increase of dose.
boolean
C0009079 (UMLS CUI [1,1])
C0205360 (UMLS CUI [1,2])
alcohol or substance abuse
Item
subjects with significant alcohol or substance abuse in the past 3 months.
boolean
C0038586 (UMLS CUI [1])
risperidone augmentation
Item
subjects with a previous trial of risperidone augmentation of clozapine
boolean
C0073393 (UMLS CUI [1,1])
C0442805 (UMLS CUI [1,2])
C0205156 (UMLS CUI [1,3])
pregnancy and contraceptive methods
Item
subjects who are pregnant, breast-feeding, or women of child-bearing potential not using adequate contraception
boolean
C0032961 (UMLS CUI [1])
C0700589 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
anticonvulsants
Item
subjects requiring treatment with anticonvulsants.
boolean
C0003286 (UMLS CUI [1])
allergy to risperidone
Item
subjects with known hypersensitivity or allergy to risperidone.
boolean
C0020517 (UMLS CUI [1,1])
C0073393 (UMLS CUI [1,2])
contraindications to continued clozapine treatment
Item
subjects with hematological or other contraindications to continued clozapine treatment.
boolean
C1301624 (UMLS CUI [1,1])
C0009079 (UMLS CUI [1,2])