schizophrenia
Item
dsm-iv criteria for schizophrenia or schizoaffective disorder
boolean
C0036341 (UMLS CUI [1])
clozapine treatment
Item
current clozapine treatment
boolean
C0009079 (UMLS CUI [1])
moderate illness severity and inadequate positive symptom
Item
moderate illness severity and inadequate positive symptom response to clozapine treatment
boolean
C0036341 (UMLS CUI [1,1])
C1547226 (UMLS CUI [1,2])
C0009079 (UMLS CUI [2,1])
C0871261 (UMLS CUI [2,2])
C0205412 (UMLS CUI [2,3])
clozapine treatment
Item
6 month period of clozapine treatment with documented clozapine blood level greater than or equal to 350 ng/ml or clozapine and norclozapine blood level greater than or equal to 450 ng/ml
boolean
C0009079 (UMLS CUI [1,1])
C0005768 (UMLS CUI [1,2])
C0068971 (UMLS CUI [2,1])
C0005768 (UMLS CUI [2,2])
organic brain disorder
Item
organic brain disorder
boolean
C0006111 (UMLS CUI [1,1])
C0747055 (UMLS CUI [1,2])
mental retardation
Item
mental retardation
boolean
C0025362 (UMLS CUI [1])
medical condition could alter the presentation or treatment
Item
medical condition whose pathology or treatment could alter the presentation or treatment of schizophrenia or significantly increase the risk associated with the proposed treatment protocol
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
pregnancy
Item
pregnancy
boolean
C0032961 (UMLS CUI [1])
current alcohol or substance dependence
Item
dsm-iv criteria for current alcohol or substance dependence within the last 6 months or dsm-iv criteria for alcohol or substance abuse within the last month
boolean
C0038586 (UMLS CUI [1])
adjunctive risperidone
Item
previously received adjunctive risperidone (at doses greater than or equal to 8 mg/day) with their clozapine treatment for greater than or equal to 6 weeks
boolean
C0073393 (UMLS CUI [1,1])
C3858690 (UMLS CUI [1,2])