Eligibility Alzheimer Disease NCT00486044

Inclusion Criteria
Description

Inclusion Criteria

Alias
UMLS CUI
C1512693
age 35 to 69
Description

age

Data type

boolean

Alias
UMLS CUI [1]
C0001779
parent with alzheimer's disease
Description

alzheimers disease

Data type

boolean

Alias
UMLS CUI [1]
C0002395
Exclusion Criteria
Description

Exclusion Criteria

Alias
UMLS CUI
C0680251
current use of cholesterol lowering medication
Description

cholesterol lowering medications

Data type

boolean

Alias
UMLS CUI [1]
C0003277
history of liver disease
Description

liver disease

Data type

boolean

Alias
UMLS CUI [1]
C0023895
history of adverse reaction to statin medications
Description

statin adverse reaction

Data type

boolean

Alias
UMLS CUI [1]
C0570410
history of previous lumbar spine surgery
Description

lumbar spine surgery

Data type

boolean

Alias
UMLS CUI [1]
C0408578
elevated lab values (creatine kinase and creatinine)
Description

creatine kinase; creatinine

Data type

boolean

Alias
UMLS CUI [1]
C0201973
UMLS CUI [2]
C0201975
use of prohibited medications: simvastatin, pravastatin, cholestyramine, lovastatin, colestipol, gemfibrozil, niacin, atorvastatin, fluvastatin, fenofibrate, rosuvastatin, clarithromycin, cyclosporine, digoxin, erythromycin, itraconazole, ketaconazole, fluconazole, nefazodone, warfarin, saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, amiodarone, verapamil
Description

concomitant medications simvastatin pravastatin cholestyramine

Data type

boolean

Alias
UMLS CUI [1,1]
C2347852
UMLS CUI [1,2]
C0074554
UMLS CUI [1,3]
C0085542
UMLS CUI [1,4]
C0008402
history of dementia
Description

dementia

Data type

boolean

Alias
UMLS CUI [1]
C0497327
currently pregnant
Description

pregnant

Data type

boolean

Alias
UMLS CUI [1]
C0549206
use of large quantities of grapefruit juice (more than 1 quart per day)
Description

grapefruit juice compliance

Data type

boolean

Alias
UMLS CUI [1,1]
C0452456
UMLS CUI [1,2]
C1321605
current involvement in another investigational drug study
Description

Study Subject Participation Status

Data type

boolean

Alias
UMLS CUI [1]
C2348568
contraindications to mri
Description

contraindication mri

Data type

boolean

Alias
UMLS CUI [1,1]
C1301624
UMLS CUI [1,2]
C0024485

Similar models

Eligibility Alzheimer Disease NCT00486044

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
C1512693 (UMLS CUI)
age
Item
age 35 to 69
boolean
C0001779 (UMLS CUI [1])
alzheimers disease
Item
parent with alzheimer's disease
boolean
C0002395 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
cholesterol lowering medications
Item
current use of cholesterol lowering medication
boolean
C0003277 (UMLS CUI [1])
liver disease
Item
history of liver disease
boolean
C0023895 (UMLS CUI [1])
statin adverse reaction
Item
history of adverse reaction to statin medications
boolean
C0570410 (UMLS CUI [1])
lumbar spine surgery
Item
history of previous lumbar spine surgery
boolean
C0408578 (UMLS CUI [1])
creatine kinase; creatinine
Item
elevated lab values (creatine kinase and creatinine)
boolean
C0201973 (UMLS CUI [1])
C0201975 (UMLS CUI [2])
concomitant medications simvastatin pravastatin cholestyramine
Item
use of prohibited medications: simvastatin, pravastatin, cholestyramine, lovastatin, colestipol, gemfibrozil, niacin, atorvastatin, fluvastatin, fenofibrate, rosuvastatin, clarithromycin, cyclosporine, digoxin, erythromycin, itraconazole, ketaconazole, fluconazole, nefazodone, warfarin, saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, amiodarone, verapamil
boolean
C2347852 (UMLS CUI [1,1])
C0074554 (UMLS CUI [1,2])
C0085542 (UMLS CUI [1,3])
C0008402 (UMLS CUI [1,4])
dementia
Item
history of dementia
boolean
C0497327 (UMLS CUI [1])
pregnant
Item
currently pregnant
boolean
C0549206 (UMLS CUI [1])
grapefruit juice compliance
Item
use of large quantities of grapefruit juice (more than 1 quart per day)
boolean
C0452456 (UMLS CUI [1,1])
C1321605 (UMLS CUI [1,2])
Study Subject Participation Status
Item
current involvement in another investigational drug study
boolean
C2348568 (UMLS CUI [1])
contraindication mri
Item
contraindications to mri
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])