Follicular b-cell lymphoma: Disease status
Item
1. histologically confirmed follicular b-cell lymphoma. this can include relapsed patients, who have had no prior rituximab therapy, or previously untreated patients. previously untreated patients should be made aware of higher priority protocols such as combination chemo-immunotherapy protocols, but if they decline that, they can be entered on this protocol.
boolean
C0024301 (UMLS CUI [1])
C0277556 (UMLS CUI [2])
C0393022 (UMLS CUI [3,1])
C0332155 (UMLS CUI [3,2])
C0332155 (UMLS CUI [4])
Patient status
Item
2. males or females, 18 years or older; expected survival of =/> 4 months; performance status of 0, 1 or 2.
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0023671 (UMLS CUI [3])
C1518965 (UMLS CUI [4])
Monoclonal cluster of differentiation cd20-positive b-cells
Item
3. demonstrable monoclonal cluster of differentiation antigen 20 (cd20)-positive b-cell population.
boolean
C0746619 (UMLS CUI [1,1])
C0054946 (UMLS CUI [1,2])
C0004561 (UMLS CUI [1,3])
Hematologic function
Item
4. acceptable hematologic status including:
boolean
C0221130 (UMLS CUI [1])
Hemoglobin
Item
i. hemoglobin (hgb) =/> 8.0 gm/dl
boolean
C0518015 (UMLS CUI [1])
White blood count
Item
ii. white blood count (wbc) =/> 3.0 x 10^3/mm^3(x 10^9/l)
boolean
C0023508 (UMLS CUI [1])
Absolute granulocyte count
Item
iii. absolute granulocyte count =/> 1.5 x 10^3/mm^3
boolean
C0857490 (UMLS CUI [1])
Platelet count
Item
iv. platelet count =/>75 x 10^3/mm^3
boolean
C0032181 (UMLS CUI [1])
Serum creatinine
Item
e. adequate renal function (serum creatinine ≤ 2mg/dl)
boolean
C0201976 (UMLS CUI [1])
CNS lymphoma
Item
1. presence of central nervous system (cns) lymphoma
boolean
C0280803 (UMLS CUI [1])
CLL
Item
2. chronic lymphocytic leukemia (cll)
boolean
C0023434 (UMLS CUI [1])
Small lymphocytic lymphoma
Item
3. small lymphocytic lymphoma
boolean
C0855095 (UMLS CUI [1])
Therapy start date
Item
4. therapy in prior 3 weeks (6 weeks for nitrosourea; 6 months for bone marrow transplantation (bmt))
boolean
C2114713 (UMLS CUI [1])
Rituximab or other anti-cd20 therapy
Item
5. patients who received prior rituximab or other anti-cd20 therapy
boolean
C0393022 (UMLS CUI [1])
C3891557 (UMLS CUI [2])
Malignancies
Item
6. serious non-malignant disease, or other malignancy
boolean
C0006826 (UMLS CUI [1])
Infection
Item
7. active infection
boolean
C0009450 (UMLS CUI [1])
HIV infection
Item
8. history of hiv infection
boolean
C0019693 (UMLS CUI [1])
Pregnancy
Item
i pregnancy
boolean
C0032961 (UMLS CUI [1])