group
Item
group c:
boolean
C1257890 (UMLS CUI [1])
age
Item
male and female subjects between the ages of 18 and 70 years
boolean
C0001779 (UMLS CUI [1])
history of asthma
Item
history of asthma
boolean
C0262926 (UMLS CUI [1,1])
C0004096 (UMLS CUI [1,2])
inhaled corticosteroids
Item
continuous treatment with inhaled corticosteroids for at least the 6-week
boolean
C2065041 (UMLS CUI [1,1])
C0040223 (UMLS CUI [1,2])
hyperreactivity to methacholine
Item
hyperreactivity to methacholine (provocative concentration of methacholine causing a 20% drop in forced expiratory volume in 1 second (pc20 fev1) methacholine ≤ 16.0 mg/ml).
boolean
C1096470 (UMLS CUI [1])
C0748133 (UMLS CUI [2])
history of asthma
Item
history of asthma
boolean
C0262926 (UMLS CUI [1,1])
C0004096 (UMLS CUI [1,2])
oral or inhaled corticosteroids
Item
no use of oral or inhaled corticosteroids for the treatment of asthma in the past 6 weeks
boolean
C2065041 (UMLS CUI [1])
C0001617 (UMLS CUI [2,1])
C0442027 (UMLS CUI [2,2])
C0040223 (UMLS CUI [3])
hyperreactivity to methacholine
Item
hyperreactivity to methacholine (pc20 fev1 methacholine ≤ 8.0 mg/ml).
boolean
C1096470 (UMLS CUI [1])
C0748133 (UMLS CUI [2])
symptoms beta agonist use or fev1
Item
at least one of the following symptoms, beta agonist use, or fev1 criteria:
boolean
C1457887 (UMLS CUI [1])
C0001644 (UMLS CUI [2])
C0748133 (UMLS CUI [3])
asthma symptoms
Item
asthma symptoms on at least two days per week; or
boolean
C0004096 (UMLS CUI [1,1])
C1457887 (UMLS CUI [1,2])
beta agonist use
Item
beta agonist use on at least two days per week; or
boolean
C0001644 (UMLS CUI [1])
fev1
Item
forced expiratory volume in 1 second (fev1) < 85% predicted
boolean
C0748133 (UMLS CUI [1])
non-smokers smoking history
Item
subjects must be non-smokers (patients who have never smoked or patients who have not smoked for 1 year and have a total pack-year smoking history < 15 packs).
boolean
C0337672 (UMLS CUI [1])
C1519384 (UMLS CUI [2])
C1277691 (UMLS CUI [3])