age postmenopausal state contraception
Item
1. male or female (medically or surgically postmenopausal or practicing an accepted form of barrier or hormonal contraception) subjects between 18 - 80 years.
boolean
C0001779 (UMLS CUI [1])
C0232970 (UMLS CUI [2])
C0700589 (UMLS CUI [3])
exacerbation of obstructive airway disease
Item
2. any severity of exacerbation of obstructive airway disease attending the outpatient clinic.
boolean
C0600260 (UMLS CUI [1,1])
C0235874 (UMLS CUI [1,2])
3. history of at least two exacerbations in the past 12 months prior to recruitment that required a course of prednisone or antibiotic or long acting bronchodilator or inhaled corticosteroid, in addition to the daily maintenance therapy
Item
3. history of at least two exacerbations in the past 12 months prior to recruitment that required a course of prednisone or antibiotic or long acting bronchodilator or inhaled corticosteroid, in addition to the daily maintenance therapy.
boolean
C0235874 (UMLS CUI [1])
C0032952 (UMLS CUI [2])
C0003232 (UMLS CUI [3])
C0006280 (UMLS CUI [4])
C0586793 (UMLS CUI [5])
written informed consent
Item
4. signed written informed consent to participate in the protocol and ability to return to the outpatient clinic for repeated clinic visits.
boolean
C0021430 (UMLS CUI [1])
exacerbation hospitalization
Item
1. if the exacerbation is severe enough to warrant hospitalization.
boolean
C0235874 (UMLS CUI [1])
C0019993 (UMLS CUI [2])
active malignancy
Item
2. active malignancy.
boolean
C0205177 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
significant gastrointestinal, hematological, cardiovascular or cerebrovascular disorder that would affect compliance
Item
3. significant gastrointestinal, hematological, cardiovascular or cerebrovascular disorder that would affect compliance with follow up visits.
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
lung surgery
Item
4. recent (within the past 2 months) or planned (within the study period) lung surgery.
boolean
C0038903 (UMLS CUI [1])
psychosis, alcoholism, active substance abuse or any personality disorder that would make compliance with the follow up visits problematic
Item
5. psychosis, alcoholism, active substance abuse or any personality disorder that would make compliance with the follow up visits problematic.
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
pregnancy or lactation
Item
6. pregnant or nursing females, as this could affect the compliance during the trial.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
any other medical or social condition, which in the opinion of the investigator could confound the interpretation of the data derived from this study
Item
7. any other medical or social condition, which in the opinion of the investigator could confound the interpretation of the data derived from this study.
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])