age
Item
age ≥ 18 years
boolean
C0001779 (UMLS CUI [1])
moderate to severe asthma
Item
moderate to severe asthma based on canadian asthma consensus report
boolean
C0581125 (UMLS CUI [1])
C0581126 (UMLS CUI [2])
airway hyper-responsiveness
Item
objective evidence of airway hyper-responsiveness (reversible airflow obstruction or positive methacholine challenge in previous two years
boolean
C0035228 (UMLS CUI [1])
inhaled corticosteroid therapy
Item
on chronic maintenance inhaled corticosteroid therapy.
boolean
C0586793 (UMLS CUI [1])
asthma exacerbation
Item
asthma exacerbation within preceding 3 months necessitating any escalation of maintenance medications
boolean
C0349790 (UMLS CUI [1])
oral prednisone
Item
chronic oral prednisone use
boolean
C0087111 (UMLS CUI [1,1])
C3216040 (UMLS CUI [1,2])
comorbidity
Item
other respiratory, inflammatory and autoimmune disorder
boolean
C0009488 (UMLS CUI [1])
creatinine kinase, liver transaminases, or renal disease
Item
abnormal baseline creatinine kinase, liver transaminases, or renal disease
boolean
C0201973 (UMLS CUI [1])
C0002594 (UMLS CUI [2])
C0022658 (UMLS CUI [3])
statin therapy
Item
history of coronary artery disease, hyperlipidemia, or other condition requiring statin therapy
boolean
C0360714 (UMLS CUI [1])