age
Item
ages 18-50, males and females
boolean
C0001779 (UMLS CUI [1])
asthma
Item
physician diagnosis of asthma; requires daily asthma medication
boolean
C0004096 (UMLS CUI [1])
moderate persistent asthma
Item
moderate persistent disease (naepp guidelines)
boolean
C1960047 (UMLS CUI [1])
fev1
Item
fev1 65 to 90% of predicted
boolean
C0748133 (UMLS CUI [1])
fev1 albuterol or metacholine challenge
Item
at least 12% increase in fev1 15-30 minutes after inhaling 2-4 puffs of albuterol or positive methacholine challenge (20% fall in fev1 at less than 8 mg/ml) - either of these can available from the previous 2 years
boolean
C0748133 (UMLS CUI [1,1])
C0001927 (UMLS CUI [1,2])
C0430567 (UMLS CUI [2,1])
C1446409 (UMLS CUI [2,2])
good health
Item
generally good health
boolean
C0018759 (UMLS CUI [1,1])
C0205170 (UMLS CUI [1,2])
oral corticosteroid
Item
oral corticosteroid use within the past 3 months
boolean
C0149783 (UMLS CUI [1,1])
C0040223 (UMLS CUI [1,2])
inhaled corticosteroids
Item
use of high dose inhaled corticosteroids (greater than 500 mcg of fluticasone per day or greater)
boolean
C2065041 (UMLS CUI [1])
smoking status
Item
current or former smoker (quit less than 6 months prior to study enrollment or greater than 10 pack years)
boolean
C1519386 (UMLS CUI [1])
C1277691 (UMLS CUI [2])
asthma exacerbation
Item
recent asthma exacerbation (within 6 weeks)
boolean
C0349790 (UMLS CUI [1])
soy isoflavone supplements
Item
current consumption of soy isoflavone supplements
boolean
adverse reaction to genistein, other phytoestrogens, or soy products
Item
known adverse reaction to genistein, other phytoestrogens, or soy products
boolean
C0020517 (UMLS CUI [1,1])
C0061202 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0071011 (UMLS CUI [2,2])
C2136331 (UMLS CUI [3])
pregnant
Item
pregnant
boolean
C0032961 (UMLS CUI [1])
unintentional weight loss
Item
unintentional weight loss of more than 10 pounds within the year
boolean
C2363736 (UMLS CUI [1])
comorbidity
Item
major or unstable medical condition
boolean
C0009488 (UMLS CUI [1])
use of an investigational drug
Item
use of an investigational drug in the previous 30 days
boolean
C0013230 (UMLS CUI [1,1])
C0040223 (UMLS CUI [1,2])