gender; age; ethnicity
Item
males and females, from all racial and ethnic categories between the ages of 60-80 years of age, with english as their first language.
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0015031 (UMLS CUI [3])
residence
Item
residents of the new york city metropolitan area.
boolean
C0237096 (UMLS CUI [1])
education
Item
minimum of 12 years of education.
boolean
C0013658 (UMLS CUI [1])
cognitive impairment ; Aging; alzheimers disease; frontotemporal dementia
Item
participants will be grouped according to the following classifications: normal aging, mild cognitive impairment (mci), alzheimer's disease (ad), or frontotemporal dementia (ftd).
boolean
C0009241 (UMLS CUI [1])
C0001811 (UMLS CUI [2])
C0002395 (UMLS CUI [3])
C0338451 (UMLS CUI [4])
genotyping; dna banking
Item
participants will agree to apoe genotyping and dna banking.
boolean
C1285573 (UMLS CUI [1])
C0872147 (UMLS CUI [2])
brain trauma; stroke; hydrocephalus; lacunar infarcts; seizures; neurological disorder.
Item
past history or mri evidence of brain damage including significant trauma, stroke, hydrocephalus, lacunar infarcts, seizures, mental retardation or serious neurological disorder.
boolean
C0876926 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
C0020255 (UMLS CUI [3])
C0333559 (UMLS CUI [4])
C0036572 (UMLS CUI [5])
C0027765 (UMLS CUI [6])
Substance Use Disorder
Item
significant history of alcoholism or drug abuse.
boolean
C0038586 (UMLS CUI [1])
psychiatric illness schizophrenia
Item
history of psychiatric illness (e.g., schizophrenia, mania or depression).
boolean
C0004936 (UMLS CUI [1,1])
C0036341 (UMLS CUI [1,2])
neuropathology
Item
any focal signs or significant neuropathology.
boolean
C0876934 (UMLS CUI [1])
cerebrovascular disease; hachinski ischemia scale
Item
a score of 4 or greater on the modified hachinski ischemia scale suggesting cerebrovascular disease.
boolean
C0007820 (UMLS CUI [1])
C0475492 (UMLS CUI [2])
hamilton depression scale
Item
a total score of 16 or more on the hamilton depression scale to exclude possible cases of primary depression.
boolean
C0451203 (UMLS CUI [1])
hypertension; cardiac disease; pulmonary disease; Vascular Diseases; metabolic disease; Hematological Disease
Item
evidence of clinically relevant and uncontrolled hypertensive, cardiac, pulmonary, vascular, metabolic or hematologic conditions.
boolean
C0020538 (UMLS CUI [1])
C0018799 (UMLS CUI [2])
C0024115 (UMLS CUI [3])
C0042373 (UMLS CUI [4])
C0025517 (UMLS CUI [5])
C0018939 (UMLS CUI [6])
physical impairment
Item
physical impairment of such severity as to adversely affect the validity of psychological testing.
boolean
C0231171 (UMLS CUI [1])
compliance behaviour
Item
hostility or refusal to cooperate.
boolean
C1321605 (UMLS CUI [1])
prosthetic devices pacemaker ; mri
Item
any prosthetic devices (e.g., pacemaker or surgical clips) that could be affected by the magnetic field employed during mri imaging.
boolean
C0175649 (UMLS CUI [1,1])
C0030163 (UMLS CUI [1,2])
C0024485 (UMLS CUI [2])
family history dementia
Item
history of familial early onset dementia.
boolean
C0241889 (UMLS CUI [1,1])
C0497327 (UMLS CUI [1,2])