age
Item
aged 70 years or older.
boolean
C0001779 (UMLS CUI [1])
family history dementia alzheimers disease senility
Item
family history of parent, brother, or sister who has, or had, serious age-related memory loss, senility, dementia, or alzheimer's disease.
boolean
C0241889 (UMLS CUI [1,1])
C0497327 (UMLS CUI [1,2])
C0002395 (UMLS CUI [1,3])
C0231337 (UMLS CUI [1,4])
cognitive status
Item
study partner available to provide information on the cognitive status of the participant and to assist with monitoring of trial medications, if needed.
boolean
C0945985 (UMLS CUI [1])
english speaking; neuropsychological testing
Item
sufficient fluency in written and spoken english to participate in study visits and neuropsychological testing.
boolean
C0376245 (UMLS CUI [1])
C0027902 (UMLS CUI [2])
vitamin e; nsaid; histamine h2 receptor antagonists; corticosteroids; aspirin; Ginkgo biloba extract
Item
willingness to limit use of the following for the duration of the study: vitamin e (at doses greater than 400 iu per day), non-aspirin nsaids, histamine h2 receptor antagonists (tagamet, for example), corticosteroids, anti-inflammatory or analgesic doses of aspirin (greater than 81 mg per day), ginkgo biloba extracts
boolean
C0042874 (UMLS CUI [1])
C0003211 (UMLS CUI [2])
C0019593 (UMLS CUI [3])
C0001617 (UMLS CUI [4])
C0004057 (UMLS CUI [5])
C0772125 (UMLS CUI [6])
compliance behaviour
Item
ability and intention to participate in regular study visits, in the opinion of the study physician.
boolean
C1321605 (UMLS CUI [1])
informed consent
Item
provision of informed consent.
boolean
C0021430 (UMLS CUI [1])
peptic ulcer disease
Item
history of peptic ulcer disease with bleeding or obstruction.
boolean
C0030920 (UMLS CUI [1])
liver disease; kidney disease
Item
clinically significant liver or kidney disease.
boolean
C0023895 (UMLS CUI [1])
C0022658 (UMLS CUI [2])
hypersensitivity aspirin ibuprofen nsaids
Item
history of hypersensitivity to aspirin, ibuprofen, celecoxib, naproxen, or other nsaids.
boolean
C0020517 (UMLS CUI [1,1])
C0004057 (UMLS CUI [1,2])
C0020740 (UMLS CUI [1,3])
C0003211 (UMLS CUI [1,4])
anti-coagulant
Item
use of anti-coagulant medication.
boolean
C0003280 (UMLS CUI [1])
cognitive impairment; dementia
Item
cognitive impairment or dementia.
boolean
C1839000 (UMLS CUI [1])
C0497327 (UMLS CUI [2])
alcohol abuse
Item
current alcohol abuse or dependence
boolean
C0085762 (UMLS CUI [1])