age: 14~60 years old;no gender limit.

diagnosis: according to the diagnosis standards of aml( with the exception of m3 ) ( according to 2008 who diagnosis criteria of aml)

performance status is not bad with eastern cooperative oncology group (ecog) score

Written informed consent obtained prior to the initiation of any study related procedures

chronic myelogenous leukemia (cml) in crisis phase.

aml transformed from other myeloproliferative diseases.

Patient is accompanied with other progressing neoplasms.

With severe malfunction of liver, lungs, kidneys or heart: the plasma levels of direct bilirubin, indirect bilirubin, alanine transaminase, aspartate transaminase and serum creatinine all are 2 times higher than normal, cardiac function is above grade ii.

Infection