female; age
Item
females who are currently physically well and between 45 and 55 years of age
boolean
C0015780 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
dsm-iv; depression
Item
current dsm-iv diagnosis of depression disorder
boolean
C0220952 (UMLS CUI [1])
C0011570 (UMLS CUI [2])
informed consent
Item
able to give informed consent
boolean
C0021430 (UMLS CUI [1])
perimenopausal
Item
perimenopausal as determined by symptom profile on the stages of reproductive aging workshop and gonadal hormonal profile
boolean
C3839366 (UMLS CUI [1])
Hypothalamic-pituitary-gonadal axis dysfunction; thyroid dysfunction; cns neoplasm; Thromboembolism of vein; breast pathology; vaginal bleeding
Item
known abnormalities in the hypothalamic-pituitary gonadal axis, thyroid dysfunction, central nervous system tumours, active or past history of a venous thromboembolic event, breast pathology, undiagnosed vaginal bleeding or abnormal pap smear results in the previous 2 years.
boolean
C2711580 (UMLS CUI [1])
C0348024 (UMLS CUI [2])
C0085136 (UMLS CUI [3])
C1997614 (UMLS CUI [4])
C3258885 (UMLS CUI [5])
C2979982 (UMLS CUI [6])
epilepsy; diabetes; Heart Diseases; renal disease; Liver diseases
Item
patients with any significant unstable medical illness such as epilepsy and diabetes or known active cardiac, renal or liver disease; or the presence of illness causing immobilisation.
boolean
C0014544 (UMLS CUI [1])
C0011847 (UMLS CUI [2])
C0018799 (UMLS CUI [3])
C0022658 (UMLS CUI [4])
C0023895 (UMLS CUI [5])
antidepressants; electroconvulsive therapy; transcranial magnetic stimulation; psychotherapy
Item
patients receiving treatment for depression including antidepressant medications, electroconvulsive therapy (ect) / transcranial magnetic stimulation (tms), formal psychotherapy or counselling, within the past 6 months
boolean
C0003289 (UMLS CUI [1])
C0013806 (UMLS CUI [2])
C0436548 (UMLS CUI [3])
C0033968 (UMLS CUI [4])
melancholia; Suicidality; hospitalisation
Item
patients experiencing severe melancholia, neurovegetative symptoms or current suicidality necessitating acute hospitalisation or intensive psychiatric treatment.
boolean
C0025193 (UMLS CUI [1])
C3166387 (UMLS CUI [2])
C0019993 (UMLS CUI [3])
psychotic symptoms; schizophrenia; bipolar disorder
Item
patients with psychotic symptoms or past history of severe mental illness including schizophrenia, and bipolar disorder.
boolean
C0871189 (UMLS CUI [1])
C0036341 (UMLS CUI [2])
C0005586 (UMLS CUI [3])
hormonal therapy tibolone
Item
use of any form of estrogen, progestin or androgen as hormonal therapy, or antiandrogen including tibolone or use of phytoestrogen supplements as powder or tablet
boolean
C0279025 (UMLS CUI [1,1])
C0076660 (UMLS CUI [1,2])
pregnancy; lactating
Item
pregnancy / lactation
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
smoking
Item
smoking cigarettes and other nicotine products.
boolean
C1519386 (UMLS CUI [1])
Substance Use Disorder
Item
illicit drug use and more than 3 standard drinks per day
boolean
C0038586 (UMLS CUI [1])