schizophrenia
Item
rdc diagnosis of schizophrenia
boolean
C0036341 (UMLS CUI [1])
Gender
Item
men and women, without regard to race/ethnicity,
boolean
C0079399 (UMLS CUI [1])
Age
Item
aged 18-45
boolean
C0001779 (UMLS CUI [1])
acute psychotic, brief psychotic rating scale score
Item
acutely psychotic with a score of at least 3 on one of the psychotic scale items of the brief psychiatric rating scale (bprs) (hallucinations, delusions, conceptual disorganization) and a total bprs of > 21 (on a 0 - 6 scale);
boolean
C0281774 (UMLS CUI [1])
C0029941 (UMLS CUI [2])
neuroleptic drugs
Item
require treatment with neuroleptic drugs on a clinical basis;
boolean
C0040615 (UMLS CUI [1])
informed consent
Item
the patient (or the patient's authorized legal representative) must understand the nature of the study and sign the informed consent;
boolean
C0021430 (UMLS CUI [1])
first psychotic episode in pschotic disorder
Item
be within the first episode of a psychotic disorder;
boolean
C0033975 (UMLS CUI [1,1])
C0237811 (UMLS CUI [1,2])
neuroleptic treatment
Item
have a history of neuroleptic treatment of < 12 weeks;
boolean
C0040615 (UMLS CUI [1])
likely to remain in the study for 2 years
Item
likely to remain in the study for 2 years.
boolean
C1321605 (UMLS CUI [1])
substance dependence
Item
substance dependence in the last six months
boolean
C0038586 (UMLS CUI [1])
seizures, blood dyscrasia
Item
history of seizure or blood dyscrasia
boolean
C0036572 (UMLS CUI [1])
C0018939 (UMLS CUI [2])
major medical illness
Item
major medical illness
boolean
C0009488 (UMLS CUI [1])
pregnancy or lactation
Item
pregnancy or lactation
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])