LVEF
Item
LVEF ≤35%
boolean
C0428772 (UMLS CUI [1])
aortic valve stenosis
Item
Aortic valve stenosis with an aortic valve area <1 cm2 (<0,6 cm3/m2)
boolean
C0003507 (UMLS CUI [1])
age
Item
Males or females at least 18 years of age
boolean
C0001779 (UMLS CUI [1])
logistic euroSCORE
Item
Logistic EuroSCORE ≥15% and age ≥75 years or if age <75 years: logistic EuroSCORE ≥20% and/or a significant contraindication for open heart surgery (e.g., porcelain aorta or severe COPD)
boolean
C3164744 (UMLS CUI [1])
signed informed consent
Item
Signed informed consent
boolean
C0021430 (UMLS CUI [1])
ICD
Item
Patients with a device regulating the heart rhythm by pacing (e.g. pacemaker, resynchronization device, implanted defibrillator) with atrioventricular block >= 1. degree and ventricular pacing rate > 10%
boolean
C0162589 (UMLS CUI [1])
C0004245 (UMLS CUI [2])
C2016308 (UMLS CUI [3])
implanted pacemaker or CRT
Item
Patients with implanted pacemaker because of AV block >= Degree II or Cardiac Resynchronization Therapy (CRT)
boolean
C0030163 (UMLS CUI [1])
C0004245 (UMLS CUI [2])
C1167956 (UMLS CUI [3])
mental disorder or drug addiction
Item
Lack of written informed consent, severe mental disorder, drug/alcohol addiction
boolean
C0021430 (UMLS CUI [1])
C1321605 (UMLS CUI [2,1])
C0439801 (UMLS CUI [2,2])
C0009488 (UMLS CUI [2,3])
C0038586 (UMLS CUI [3])
life expectancy
Item
Life expectancy < 1 year
boolean
C0023671 (UMLS CUI [1])
hypersensibility or contraindication
Item
Hypersensitivity or contraindication to acetyl salicyl acid, heparin, ticlopidine, clopidogrel, nitinol or sensitivity to contrast media that cannot be adequately premedicated
boolean
C0020517 (UMLS CUI [1,1])
C0004057 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0019134 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0040207 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C0070166 (UMLS CUI [4,2])
C0020517 (UMLS CUI [5,1])
C0068790 (UMLS CUI [5,2])
C0020517 (UMLS CUI [6,1])
C0009924 (UMLS CUI [6,2])
myocardial infarction
Item
Recent myocardial infarction (STEMI within the last 3 months)
boolean
C0027051 (UMLS CUI [1])
left ventricular or atrial thrombus
Item
Left ventricular or atrial thrombus
boolean
C0587044 (UMLS CUI [1])
C0741299 (UMLS CUI [2])
uncontrolled atrial fibrillation
Item
Uncontrolled atrial fibrillation (heart rate > 140/Min)
boolean
C0004238 (UMLS CUI [1,1])
C0021311 (UMLS CUI [1,2])
mitral or tricuspidal valvular insufficiency
Item
Mitral or tricuspidal valvular insufficiency (> grade II)
boolean
C0026266 (UMLS CUI [1])
C0040961 (UMLS CUI [2])
aortic valve replacement
Item
Previous aortic valve replacement with mechanical valve
boolean
C0003506 (UMLS CUI [1])
cerebrovascular event
Item
Evolutive or recent cerebrovascular event (within the last 3 months)
boolean
C0038454 (UMLS CUI [1])
inadequate catheter
Item
Vascular conditions that make insertion and endovascular access to the aortic valve impossible
boolean
C0021430 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C2712690 (UMLS CUI [1,3])
symptomatic carotid
Item
Symptomatic carotid or vertebral arterial narrowing (>70%) disease
boolean
C0007282 (UMLS CUI [1])
C0042568 (UMLS CUI [2])
abdominal or thoracic aortic aneurysm
Item
Abdominal or thoracic aortic aneurysm in the path of the delivery system
boolean
C0162871 (UMLS CUI [1])
C0162872 (UMLS CUI [2])
bleeding diathesis
Item
Bleeding diathesis or contraindication to blood transfusion
boolean
C0005779 (UMLS CUI [1])
C1301624 (UMLS CUI [2,1])
C0005841 (UMLS CUI [2,2])
active gastritis or peptic ulcer disease
Item
Active gastritis or peptic ulcer disease
boolean
C0017152 (UMLS CUI [1])
C0030920 (UMLS CUI [2])
renal function
Item
Severely impaired renal function, GFR < 30 ml/min
boolean
C1316377 (UMLS CUI [1])
sepsis or acute endocarditis
Item
Sepsis including acute endocarditis
boolean
C0243026 (UMLS CUI [1])
C0375268 (UMLS CUI [2])
partition in another trial
Item
Partition in another clinical trial
boolean
C2348568 (UMLS CUI [1])
limited compliance expectable
Item
High probability of non-compliant study participation
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
pregnancy
Item
Pregnancy
boolean
C0032961 (UMLS CUI [1])