Age
Item
patients aged 18 years or over with histologically verified adenocarcinoma of colon or rectum.
boolean
C0001779 (UMLS CUI [1])
C0009402 (UMLS CUI [2,1])
C0001418 (UMLS CUI [2,2])
recurrent disease, surgery, radiotherapy
Item
recurrent of metastatic disease not amenable to curative surgery and/or radiotherapy.
boolean
C0277556 (UMLS CUI [1,1])
C0027627 (UMLS CUI [1,2])
C0038894 (UMLS CUI [2])
C1522449 (UMLS CUI [3])
life expectancy
Item
life expectancy greater than 3 months.
boolean
C0023671 (UMLS CUI [1])
karnofsky
Item
karnofsky index score greater than or equal to 50%.
boolean
C0206065 (UMLS CUI [1])
written informed consent
Item
written informed consent obtained.
boolean
C0021430 (UMLS CUI [1])
malignancies
Item
neoplastic lesions other than colorectal cancer (except treated basal cell carcinoma of the skin or cancer of the uterine cervix, through stage i.
boolean
C0006826 (UMLS CUI [1])
C0007117 (UMLS CUI [2])
C0302592 (UMLS CUI [3])
acute intercurrent illness.
Item
acute intercurrent illness.
boolean
C0009488 (UMLS CUI [1])
patient medical risk due to systemic disease or grossly abnormal laboratory results
Item
patient considered to be a medical risk because of non-malignant systemic disease or grossly abnormal laboratory results.
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
cancer treatment
Item
patients who had received any other anticancer therapy within 3 months.
boolean
C0920425 (UMLS CUI [1])
condition affectin serum gastrin or gastric acidity
Item
factor liable to alter the serum gastrin concentration or affect intra-gastric acidity, for instance concomitant therapy with h2 receptor antagonist drugs, proton pump inhibitors, or previous gastric surgery.
boolean
C0009488 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0202036 (UMLS CUI [1,3])
C0009488 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0017120 (UMLS CUI [2,3])
immunocompromised, steroid therapy
Item
patients immunologically compromised including those on corticosteroid therapy.
boolean
C0085393 (UMLS CUI [1])
C0149783 (UMLS CUI [2])
child-bearing age
Item
women of child-bearing age.
boolean
C0079399 (UMLS CUI [1])
C3831118 (UMLS CUI [2])
C1960468 (UMLS CUI [3])
hypernsensitivity protocol agent
Item
positive immediate hypersensitivity reaction to skin testing with study medication.
boolean
C0020517 (UMLS CUI [1,1])
C1521826 (UMLS CUI [1,2])
unable to complete the diary book
Item
patients unable to complete the diary book
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
hemoglobin, white blood cell count, platelet count
Item
haematogical status haemoglobin count less than 10g/dl white blood cell count less than 4.0 x 10^9/l platelet count less than 100 x 10^9/l
boolean
C0019046 (UMLS CUI [1])
C0005821 (UMLS CUI [2])