parkinson's disease
Item
idiopathic parkinson's disease for at least 7 years with rest tremor or bradykinesia and one of the following cardinal signs: rigidity flexed posture loss of postural reflexes freezing (motor blocks)
boolean
C0030567 (UMLS CUI [1])
levodopa
Item
continuing response to levodopa
boolean
C0023570 (UMLS CUI [1])
intractable symptoms
Item
presence of at least one of the following intractable symptoms or signs: intractable disabling fluctuations intractable disabling dyskinesias intractable "on" freezing (i.e., motor blocks that interfere with walking despite being "on"
boolean
C0205269 (UMLS CUI [1])
bilateral parkinsonism
Item
bilateral parkinsonism when "off" (may be asymmetry between right and left sides)
boolean
dopa uptake
Item
decreased dopa uptake in the striatum
boolean
C0013023 (UMLS CUI [1])
brain surgery
Item
no prior brain surgery
boolean
C0195775 (UMLS CUI [1])
cardiopulmonary disease
Item
cardiovascular: no severe cardiopulmonary disease
boolean
C0009488 (UMLS CUI [1])
neurologic disorder
Item
neurologic: no history of strokes no neuroleptics no encephalitis no oculogyric crisis no remission no cerebellar signs no dementia (mini-mental state score no greater than 22) no supranuclear gaze palsy no babinski sign no orthostatic hypotension no hydrocephalus no brain tumor no occlusive cerebrovascular disease
boolean
C0027765 (UMLS CUI [1])
pulmonary pressure
Item
pulmonary: absolute standing pressure at least 90/60 mmhg
boolean
C0428642 (UMLS CUI [1])
comorbidity
Item
other: no diabetes mellitus no exposure to toxins no other severe medical disease hamilton depression scale score of less than 20 points
boolean
C0009488 (UMLS CUI [1])