rheumatology criteria for jra
Item
meet american college of rheumatology criteria for jra.
boolean
C3714757 (UMLS CUI [1])
active anterior uveitis
Item
have active anterior uveitis defined as the presence of inflammatory cells (grade 1+ or higher) in the anterior chamber of at least one eye or the current use of topical corticosteroids to control exacerbation of disease at a frequency of tid or higher.
boolean
C0042164 (UMLS CUI [1])
Age
Item
be between 2 and 18 years, inclusive.
boolean
C0001779 (UMLS CUI [1])
slit lamp biomicroscopy
Item
be able to undergo slit lamp biomicroscopy for assessment of anterior chamber cells.
boolean
C0419360 (UMLS CUI [1])
compliance
Item
be able to comply with study requirements.
boolean
C1321605 (UMLS CUI [1])
childhood immunizations
Item
be up to date on all recommended childhood immunizations.
boolean
C0020971 (UMLS CUI [1])
current arthritis regimen
Item
have been using current arthritis regimen for at least 8 weeks prior to enrollment.
boolean
C0020971 (UMLS CUI [1])
media opacity
Item
have a media opacity that precludes assessment of anterior chamber inflammation.
boolean
C0010038 (UMLS CUI [1])
periocular injection of corticosteroids
Item
have a periocular injection of corticosteroids within 2 months of baseline, or used a systemic experimental therapy within one month of baseline evaluation.
boolean
C0001617 (UMLS CUI [1])
disease modifying antirheumatic therapy
Item
be currently receiving disease modifying antirheumatic therapy (dmard), with the exception of prednisone at a dose no greater than 1.0 mg/kg/day, or methotrexate at a dose no greater than 15 mg/m(2)/week.
boolean
C0003191 (UMLS CUI [1])
C0032952 (UMLS CUI [2])
C0025677 (UMLS CUI [3])
inflammation
Item
have active eye or joint inflammation requiring immediate addition or increase in systemic anti-inflammatory medications.
boolean
C0021368 (UMLS CUI [1])
be a female who is pregnant or lactating .
Item
be a female who is pregnant or lactating .
boolean
C0032961 (UMLS CUI [1])
contraception
Item
refuse to use contraception during the study and 6 months after termination of active study therapy, if child-bearing or fathering potential exists.
boolean
C0700589 (UMLS CUI [1])
latanoprost
Item
have used latanoprost within two weeks prior to enrollment, or have a current or likely need for latanoprost during the course of the study.
boolean
C0090306 (UMLS CUI [1])
hypersensitivity to fluorescein dye
Item
have hypersensitivity to fluorescein dye.
boolean
C0020517 (UMLS CUI [1,1])
C0060520 (UMLS CUI [1,2])
infections
Item
have active serious infections or history of recurring serious infections.
boolean
C0009450 (UMLS CUI [1])
spondyloarthropathy or entheseopathy
Item
evidence of spondyloarthropathy or entheseopathy.
boolean
C0949691 (UMLS CUI [1])
C0242490 (UMLS CUI [2])