cll in biopsy or flow cytometry
Item
diagnosis of cll established by bone marrow aspiration and biopsy or flow cytometry of peripheral blood.
boolean
C0005558 (UMLS CUI [1,1])
C0023434 (UMLS CUI [1,2])
C0016263 (UMLS CUI [2,1])
C0023434 (UMLS CUI [2,2])
therapy
Item
no previous therapy for cll.
boolean
C0087111 (UMLS CUI [1])
life expectancy
Item
expected remaining life span greater than or equal to six months.
boolean
C0023671 (UMLS CUI [1])
age
Item
18 years or older.
boolean
C0001779 (UMLS CUI [1])
informed consent
Item
willingness and ability to sign an informed consent.
boolean
C0021430 (UMLS CUI [1])
malignancy
Item
other active malignancy or history of treatment of any malignancy (excluding non-melanoma skin cancer) within the previous three years.
boolean
C0006826 (UMLS CUI [1])
malignancy
Item
history of other malignancy which could affect the diagnosis or assessment of osi-461.
boolean
C0006826 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0011900 (UMLS CUI [1,3])
therapy
Item
previous therapy for cll.
boolean
C0087111 (UMLS CUI [1])
Study Subject Participation Status
Item
use of an investigational medication or device within one month of initiating study therapy.
boolean
C2348568 (UMLS CUI [1])
immunotherapy
Item
concurrent immunotherapy.
boolean
C0021083 (UMLS CUI [1])
steroids
Item
use of steroids at the time of enrollment (patients who require steroids after enrollment may remain on study).
boolean
C0038317 (UMLS CUI [1])
comorbidity, medication
Item
any condition or any medication which may interfere with the conduct of the study.
boolean
C0009488 (UMLS CUI [1])
C0013227 (UMLS CUI [2])
comorbidity
Item
serious uncontrolled intercurrent medical or psychiatric illness, including serious infection.
boolean
C0009488 (UMLS CUI [1])
cns involvement
Item
evidence of cns involvement.
boolean
C0449389 (UMLS CUI [1])
pregnancy, breastfeeding
Item
pregnant or nursing women.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])