age
Item
age: 18-65 years
boolean
C0001779 (UMLS CUI [1])
cd19 positive b cell malignancies
Item
patients with cluster of differentiation 19 (cd19) positive b cell malignancies as confirmed by flow cytometry
boolean
C2698589 (UMLS CUI [1])
recurrent disease
Item
refractory or relapsed b cell-acute lymphoblastic leukemia
boolean
C0277556 (UMLS CUI [1])
no available curative treatment options
Item
no available curative treatment options (such as hematopoietic stem cell transplantation)
boolean
C1276305 (UMLS CUI [1])
C1548671 (UMLS CUI [2])
stage iii-iv disease
Item
stage iii-iv disease
boolean
C0280425 (UMLS CUI [1,1])
C0280426 (UMLS CUI [1,2])
creatinine
Item
creatinine < 2.5 mg/dl
boolean
C0201976 (UMLS CUI [1])
aspartate transaminase-alanine transaminase ratio
Item
aspartate transaminase-alanine transaminase ratio < 3x normal
boolean
C0364051 (UMLS CUI [1])
bilirubin
Item
bilirubin < 2.0 mg/dl
boolean
C1278039 (UMLS CUI [1])
karnofsky performance status
Item
karnofsky performance status >= 60
boolean
C0206065 (UMLS CUI [1])
life expectancy
Item
expected survival time > 3 months
boolean
C0023671 (UMLS CUI [1])
venous access
Item
adequate venous access for apheresis
boolean
C0750164 (UMLS CUI [1])
informed consent
Item
ability to understand and provide informed consent
boolean
C0021430 (UMLS CUI [1])
pregnant or breastfeeding
Item
pregnant or lactating women
boolean
C0549206 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
immunosuppressive therapy
Item
patients requiring t cell immunosuppressive therapy
boolean
C0521304 (UMLS CUI [1])
cns leukemia
Item
active central nervous system leukemia
boolean
C1332884 (UMLS CUI [1])
malignancies
Item
any concurrent active malignancies
boolean
C0006826 (UMLS CUI [1])
patients with a history of a seizure disorder or cardiac disorder
Item
patients with a history of a seizure disorder or cardiac disorder
boolean
C0014544 (UMLS CUI [1])
C0018799 (UMLS CUI [2])
immunotherapy
Item
previous treatment with any immunotherapy products
boolean
C0021083 (UMLS CUI [1])
patients with human immunodeficiency virus, hepatitis b or c infection
Item
patients with human immunodeficiency virus, hepatitis b or c infection
boolean
C0019163 (UMLS CUI [1])
C0019196 (UMLS CUI [2])
C0019699 (UMLS CUI [3])
infection
Item
uncontrolled active infection
boolean
C0009450 (UMLS CUI [1])