age
Item
age ≥ 18 years.
boolean
C0001779 (UMLS CUI [1])
chronic heart failure
Item
patients with stable chronic heart failure implanted with mono-cameral or bicameral icd with a home monitoring remote control.
boolean
C0264716 (UMLS CUI [1])
left ventricular dysfunction
Item
moderate to severe left ventricular dysfunction (fe ≤ 40%).
boolean
C0242698 (UMLS CUI [1])
Heart failure
Item
any cause of heart failure was allowed apart congenital heart disease.
boolean
C0018801 (UMLS CUI [1])
pacemaker
Item
bicameral icd programmed in ddd or aai/ddd with av interval < 300 msec.
boolean
C0030163 (UMLS CUI [1])
heart rate
Item
rest ecg heart rate ≥70 bpm;
boolean
C0018810 (UMLS CUI [1])
sinus rhythm.
Item
sinus rhythm.
boolean
C0232201 (UMLS CUI [1])
lipid-lowering therapy; angiotensin-converting enzyme inhibitor; beta-blocker
Item
in therapy with low-dose of beta-blocker (bisoprolol 1,25-2,5 mg) and with the maximum dose tolerated of angiotensin-converting enzyme inhibitor or blockade of angiotensin ii receptor, mineralocorticoid antagonist, antiplatelet and lipid-lowering therapy, unless contraindicated.
boolean
C0585943 (UMLS CUI [1])
C0003015 (UMLS CUI [2])
C0001645 (UMLS CUI [3])
informed consent
Item
inability of providing informed consent;
boolean
C0021430 (UMLS CUI [1])
age
Item
age < 18 years.
boolean
C0001779 (UMLS CUI [1])
pregnant; lactating
Item
state of pregnancy or lactation.
boolean
C0549206 (UMLS CUI [1])
C2828358 (UMLS CUI [2])
myocardial infarction
Item
recent (<2 months) myocardial infarction;
boolean
C0027051 (UMLS CUI [1])
contraindications; beta-blockers
Item
contraindications to beta-blockers and ivabradine;
boolean
C0683526 (UMLS CUI [1])
C0001645 (UMLS CUI [2])
heart rate
Item
rest ecg heart rate < 70 bpm;
boolean
C0018810 (UMLS CUI [1])
sinus rhythm.
Item
no sinus rhythm.
boolean
C0232201 (UMLS CUI [1])
antiarrhythmic drugs
Item
administration of non-dihydropyridinic calcium channels antagonists, digitalis, class i antiarrhythmic drugs, strong inhibitors of cytochrome p450 3a4 at the time of enrollment.
boolean
C0003195 (UMLS CUI [1])