Subjects must have a typical anginal pain lasting at least 20 min., but no longer than 24h.

ECG confirming ischaemia

ST segment depression >= 1,0 mm in at least 2 leads

negative T waves >= 2,0 mm in at least 2 leads

Positive troponin I (TnI)

Subjects must demonstrate their willingness to participate in the study and comply with its procedures by signing a written informed consent and/or parent or legal guardian must have signed a written informed consent.

Subjects must be ≥ 21 year of age, of either sex and any race.

Women of childbearing potential (includes women who are less than 1 year postmenopausal and women who become sexually active) must be using an acceptable method of birth control (e.g., hormonal contraceptive, medically prescribed IUD - intrauterine device, condom in combination with spermicide) or be surgically sterilized (e.g., hysterectomy or tubal ligation).

Women who are pregnant or nursing.

Angina lasting longer than 24h

ST segment elevation - Pardy wave

age over 75 years

history of revascularization procedure during last 6 months (PTCA, CABG)

chronic heart failure (NYHA III or IV) during pre-hospitalization period

History of bleeding from gastrointestinal tract system during last 30 days

History of bleeding from genitourinary system during last 30 days

history of intracranial lesions or stroke

history of major surgery during last 6 weeks

history of trauma during last 6 weeks

history of hemorrhagic diathesis

thrombocytopenia < 100 000/mm3

anticoagulant therapy with INR>2,0

significant hepatic failure

significant renal failure with serum creatinine>2,0 mg%

elevated blood pressure: SBP>200mmHg and/or DBP>110mmHg despite the antihypertensive treatment

allergy to drugs or any therapeutic agent