ID

20535

Descrizione

Treatment of Depression in the Elderly; ODM derived from: https://clinicaltrials.gov/show/NCT00130455

collegamento

https://clinicaltrials.gov/show/NCT00130455

Keywords

  1. 01/03/17 01/03/17 -
Caricato su

1 marzo 2017

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY 4.0

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Eligibility Depression NCT00130455

Eligibility Depression NCT00130455

  1. StudyEvent: Eligibility
    1. Eligibility Depression NCT00130455
Inclusion Criteria
Descrizione

Inclusion Criteria

Alias
UMLS CUI
C1512693
in- or out-patients of 65 years of age or above fulfilling the international classification of diseases-tenth edition (icd-10) diagnosis of depressive single episode (f32.00-32.11. 32.8 or 32.9), depressive recurrent episode (f33.00-33.11, 33.8 or 33.9) or organic depressive episode (f06.32).
Descrizione

Age and depression

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0001779
UMLS CUI [2]
C0011581
the depressive state should be mild to moderate and reach a score on ham-d6 of ≥ 7 and ≤ 11
Descrizione

Hamilton Score

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0451203
patients with dementia can be included provided they have a mini mental state exam (mmse) score of ≥ 17
Descrizione

Mini mental state exam

Tipo di dati

boolean

Alias
UMLS CUI [1]
C2960235
Exclusion Criteria
Descrizione

Exclusion Criteria

Alias
UMLS CUI
C0680251
patients with a current depressive episode of a severity reaching a score of ≥ 12 on the ham-d6-item depression factor. this is to exclude patients with severe or psychotic depression
Descrizione

Severe or psychotic depression

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0588008
UMLS CUI [2]
C0743072
patients with suicidal thoughts or behaviour
Descrizione

Suicidal thoughts

Tipo di dati

boolean

Alias
UMLS CUI [1]
C1948150
patients with conditions where treatment with escitalopram is contraindicated: e.g. hypersensitivity to escitalopram or other contents of escitalopram tablets, concomitant treatment with non-selective, irreversible mono-amine-oxidase inhibitors, such as marplan
Descrizione

Contraindication to escitalopram

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1099456
UMLS CUI [1,2]
C1301624
patients who in the current depressive episode have had a failed trial of treatment with escitalopram
Descrizione

Failed treatment with escitalopram

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C1099456
UMLS CUI [1,2]
C0438286
co-morbid dementia with a severity corresponding to a score on the mmse of less than 17 as these patients will often be without the ability to give informed consent
Descrizione

Dementia

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0497327
patients with sensory defects rendering psychometric assessment impossible, e.g. deafness, blindness, severe aphasia
Descrizione

Sensory defects

Tipo di dati

boolean

Alias
UMLS CUI [1]
C4068865
patients who cannot speak danish well enough to make psychometric assessment possible and meaningful
Descrizione

Language

Tipo di dati

boolean

Alias
UMLS CUI [1]
C1145677
patients with congenital or early acquired intellectual deficits
Descrizione

Intellectual deficits

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0025362

Similar models

Eligibility Depression NCT00130455

  1. StudyEvent: Eligibility
    1. Eligibility Depression NCT00130455
Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
C1512693 (UMLS CUI)
Age and depression
Item
in- or out-patients of 65 years of age or above fulfilling the international classification of diseases-tenth edition (icd-10) diagnosis of depressive single episode (f32.00-32.11. 32.8 or 32.9), depressive recurrent episode (f33.00-33.11, 33.8 or 33.9) or organic depressive episode (f06.32).
boolean
C0001779 (UMLS CUI [1])
C0011581 (UMLS CUI [2])
Hamilton Score
Item
the depressive state should be mild to moderate and reach a score on ham-d6 of ≥ 7 and ≤ 11
boolean
C0451203 (UMLS CUI [1])
Mini mental state exam
Item
patients with dementia can be included provided they have a mini mental state exam (mmse) score of ≥ 17
boolean
C2960235 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
Severe or psychotic depression
Item
patients with a current depressive episode of a severity reaching a score of ≥ 12 on the ham-d6-item depression factor. this is to exclude patients with severe or psychotic depression
boolean
C0588008 (UMLS CUI [1])
C0743072 (UMLS CUI [2])
Suicidal thoughts
Item
patients with suicidal thoughts or behaviour
boolean
C1948150 (UMLS CUI [1])
Contraindication to escitalopram
Item
patients with conditions where treatment with escitalopram is contraindicated: e.g. hypersensitivity to escitalopram or other contents of escitalopram tablets, concomitant treatment with non-selective, irreversible mono-amine-oxidase inhibitors, such as marplan
boolean
C1099456 (UMLS CUI [1,1])
C1301624 (UMLS CUI [1,2])
Failed treatment with escitalopram
Item
patients who in the current depressive episode have had a failed trial of treatment with escitalopram
boolean
C1099456 (UMLS CUI [1,1])
C0438286 (UMLS CUI [1,2])
Dementia
Item
co-morbid dementia with a severity corresponding to a score on the mmse of less than 17 as these patients will often be without the ability to give informed consent
boolean
C0497327 (UMLS CUI [1])
Sensory defects
Item
patients with sensory defects rendering psychometric assessment impossible, e.g. deafness, blindness, severe aphasia
boolean
C4068865 (UMLS CUI [1])
Language
Item
patients who cannot speak danish well enough to make psychometric assessment possible and meaningful
boolean
C1145677 (UMLS CUI [1])
Intellectual deficits
Item
patients with congenital or early acquired intellectual deficits
boolean
C0025362 (UMLS CUI [1])

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