Eligibility Major Depressive Disorder NCT02078817

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
C1512693 (UMLS CUI)
Adolescent | Age
Item
male and female adolescents aged 12 to 18 years.
boolean
C0205653 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
DEPRESSIVE DISORDER MAJOR WITHOUT PSYCHOTIC FEATURE Recurrent
Item
presence of recurrent major depression without psychotic features confirmed by the k-sads-pl (kaufman et al., 1997).
boolean
C0743081 (UMLS CUI [1,1])
C2945760 (UMLS CUI [1,2])
Depressive disorder Depression in children Rating scale | Ketamine
Item
current depression severity measured by the children's depression rating scale (cdrs) (poznanski, 1985) raw score greater than or equal to 36 at screening and the day ketamine is due to be received for the first time.
boolean
C0011581 (UMLS CUI [1,1])
C3826462 (UMLS CUI [1,2])
C0681889 (UMLS CUI [1,3])
C0022614 (UMLS CUI [2])
Depressive episode Resistant to Treatment | Remission failed | Antidepressant therapy Quantity | Class pharmacological different
Item
current depressive episode resistant to treatment, defined as failure to achieve remission (elimination of symptoms and restoration of pre-morbid psychosocial functioning) from at least 2 antidepressant trials of different pharmacological classes. systematic evaluation of previous antidepressant trials will be assessed by using the antidepressant treatment history form (sackeim, 2001).
boolean
C0349217 (UMLS CUI [1,1])
C0332325 (UMLS CUI [1,2])
C0087111 (UMLS CUI [1,3])
C0544452 (UMLS CUI [2,1])
C0231175 (UMLS CUI [2,2])
C1096649 (UMLS CUI [3,1])
C1265611 (UMLS CUI [3,2])
C0456387 (UMLS CUI [4,1])
C0205464 (UMLS CUI [4,2])
C1705242 (UMLS CUI [4,3])
Antidepressant therapy Dose Stable | Ketamine
Item
if present, current antidepressant medication treatment must be dose stable for at least 2 months prior to beginning the study. (patients will continue with current antidepressant treatment throughout the study. based on our experience in current research at the va medical center using serial ketamine for adult trd, patients have shown positive results while continuing their current antidepressant treatment.)
boolean
C1096649 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0022614 (UMLS CUI [2])
Item Group
C0680251 (UMLS CUI)
Lacking Able to speak English Language
Item
inability to speak english
boolean
C0332268 (UMLS CUI [1,1])
C0564215 (UMLS CUI [1,2])
C0376245 (UMLS CUI [1,3])
Informed Consent Unable | Informed Consent Unwilling
Item
inability or unwillingness to provide written informed consent
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
C0021430 (UMLS CUI [2,1])
C0558080 (UMLS CUI [2,2])
Mental Retardation | Pervasive Development Disorder
Item
a history of mental retardation or any pervasive developmental disorder
boolean
C0025362 (UMLS CUI [1])
C0524528 (UMLS CUI [2])
Schizophrenia | Schizoaffective Disorder | Psychotic Disorder | Schizophrenia Lifetime | Schizoaffective Disorder Lifetime | Psychotic Disorder Lifetime
Item
current or lifetime diagnosis of schizophrenia, schizoaffective disorder, or psychosis nos.
boolean
C0036341 (UMLS CUI [1])
C0036337 (UMLS CUI [2])
C0033975 (UMLS CUI [3])
C0036341 (UMLS CUI [4,1])
C4071830 (UMLS CUI [4,2])
C0036337 (UMLS CUI [5,1])
C4071830 (UMLS CUI [5,2])
C0033975 (UMLS CUI [6,1])
C4071830 (UMLS CUI [6,2])
First Degree Relative Schizophrenia | First Degree Relative Schizoaffective Disorder | First Degree Relative Psychotic Disorders
Item
family history with a first degree relative with schizophrenia, schizoaffective disorder, or psychosis nos.
boolean
C1517194 (UMLS CUI [1,1])
C0036341 (UMLS CUI [1,2])
C1517194 (UMLS CUI [2,1])
C0036337 (UMLS CUI [2,2])
C1517194 (UMLS CUI [3,1])
C0033975 (UMLS CUI [3,2])
Seizures | Nervous system disorder
Item
diagnosis of seizures or other neurological disorders.
boolean
C0036572 (UMLS CUI [1])
C0027765 (UMLS CUI [2])
Comorbidity | Substance Use Disorders | Substance Dependence
Item
comorbid diagnosis of substance abuse or dependence, current or past.
boolean
C0009488 (UMLS CUI [1])
C0038586 (UMLS CUI [2])
C0038580 (UMLS CUI [3])
Illness Unstable
Item
clinically unstable medical illness.
boolean
C0221423 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
Barbiturates | Narcotics | Hypnotics High dose Sleeplessness | Exception Benzodiazepines | Zolpidem Dose
Item
current use of the following medications: any barbiturates, any narcotics, any non-benzodiazepine hypnotics at doses higher than zolpidem 10 mg qhs or equivalent for insomnia.
boolean
C0004745 (UMLS CUI [1])
C0027415 (UMLS CUI [2])
C0020591 (UMLS CUI [3,1])
C0444956 (UMLS CUI [3,2])
C0917801 (UMLS CUI [3,3])
C1705847 (UMLS CUI [4,1])
C0005064 (UMLS CUI [4,2])
C0078839 (UMLS CUI [5,1])
C0178602 (UMLS CUI [5,2])
Pregnancy
Item
for women: pregnancy (confirmed by baseline lab test).
boolean
C0032961 (UMLS CUI [1])
Medical contraindication MRI | Metals Body | Claustrophobia
Item
the presence of any mri contra-indications such as mri-incompatible metals in the body or claustrophobia.
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C0025552 (UMLS CUI [2,1])
C1318419 (UMLS CUI [2,2])
C0008909 (UMLS CUI [3])

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