For Females Of Childbearing Potential Was A Negative Serum Pregnancy Test Done (For females of childbearing potential was a negative serum pregnancy test done)
CL Item
Has The Patient Received Any Chemotherapy, Radiotherapy, Or Other Treatment Intended As An Anti-cancer Therapy Since The Protocol Based Treatment (rt, Temozolomide +/- Bevacizumab/placebo) On The Blinded Component Of The Study (Has the patient received any chemotherapy, radiotherapy, or other treatment intended as an anti-cancer therapy since the protocol based treatment (RT, temozolomide +/- bevacizumab/placebo) on the blinded component of the study)
CL Item
Has The Patient Recovered From The Effects Of Surgery, Postoperative Infection, And Other Complications (Has the patient recovered from the effects of surgery, postoperative infection, and other complications)
CL Item
Has The Patient Undergone Resection Of The Recurrent Tumor/tumors (Has the patient undergone resection of the recurrent tumor/tumors)
CL Item
If On Full Dose Anticoagulants, Have Both Of The Following Criteria Been Met No Active Bleeding Or Pathological Condition That Carries A High Risk Of Bleeding; In-range Inr On A Stable Dose Of Oral Anticoagulant (If on full dose anticoagulants, have both of the following criteria been met No active bleeding or pathological condition that carries a high risk of bleeding; In-range INR on a stable dose of oral anticoagulant)
CL Item
Is Systolic Blood Pressure <=160 Mg Hg Or Diastolic Pressure <= 90 Mg Hg (Is systolic blood pressure <=160 mg hg or diastolic pressure <= 90 mg hg)
CL Item
Is The Electrocardiogram Without Evidence Of Acute Cardiac Ischemia (Is the electrocardiogram without evidence of acute cardiac ischemia)
CL Item
Is The Karnofsky Performance Status > 60 (Is the Karnofsky performance status > 60)
CL Item
Is The Patient On Full-dose Anticoagulants (e.g., Warfarin Or Lmw Heparin) (Is the patient on full-dose anticoagulants (e.g., warfarin or LMW heparin))
CL Item
Is The Prothrombin Time/international Normalized Ratio (pt Inr) < 1.4 For Patients Not On Warfarin Confirmed By Testing (Is the prothrombin time/international normalized ratio (PT INR) < 1.4 for patients not on warfarin confirmed by testing)
CL Item
Is There Adequate Bone Marrow Function Defined As Follows Absolute Neutrophil Count (anc) >= 1,500 Cells/mm^3; Platelets >= 100,000 Cells/mm^3; Hemoglobin >= 10.0 G/dl (note: The Use Of Transfusion Or Other Intervention Is Acceptable) (Is there adequate bone marrow function defined as follows Absolute neutrophil count (ANC) >= 1,500 cells/mm^3; Platelets >= 100,000 cells/mm^3; Hemoglobin >= 10.0 g/dl (Note: The use of transfusion or other intervention is acceptable))
CL Item
Is There Adequate Hepatic Function, As Defined Below Bilirubin <= 2.0 Mg/dl; Alt/ast <= 3 X Normal Range (Is there adequate hepatic function, as defined below Bilirubin <= 2.0 mg/dl; ALT/AST <= 3 x normal range)
CL Item
Is There Adequate Renal Function, As Defined Below Bun <= 30 Mg/dl; Creatinine <= 1.7 Mg/dl; Urine Protein Screened By Urine Analysis For Urine Protein Creatinine (upc) Ratio. For Upc Ratio > 0.5, 24-hour Urine Protein Should Be Obtained (Is there adequate renal function, as defined below BUN <= 30 mg/dl; Creatinine <= 1.7 mg/dl; Urine protein screened by urine analysis for urine protein creatinine (UPC) ratio. For UPC ratio > 0.5, 24-hour urine protein should be obtained)
CL Item
Planned Start Date For Salvage Treatment (Planned start date for salvage treatment)
CL Item
Was An Mri Or Ct Scan Obtained That Demonstrates The Following: Postoperative Hemorrhage Defined As > 1 Cm Diameter Of Blood (if > 1 Cm Of Acute Blood Is Detected, The Patient May Not Receive Unblinded Bevacizumab) (Was an MRI or CT scan obtained that demonstrates the following: postoperative hemorrhage defined as > 1 cm diameter of blood (if > 1 cm of acute blood is detected, the patient may not receive unblinded bevacizumab))
CL Item
Was The Patient Diagnosed With Recurrance Or Progression (must Be Diagnosed By Imaging Only) (Was the patient diagnosed with recurrance or progression (must be diagnosed by imaging only))