Ausschlusskriterien
Evidence of symptomatic CNS lesions
boolean
Previous malignancy (other than melanoma) within the past 2 years, except for treated and controlled basal or squamous cell carcinoma of the skin or carcinoma in-situ of the cervix
boolean
Concurrent administration of any anti-cancer therapies other than those administered in the study
boolean
Clinically significant cardiovascular disease or event within the 6 months prior to first administration of study drug
boolean
Refractory nausea or vomiting, external biliary shunt, or significant bowel resection that would preclude adequate absorption
boolean