age at least 18 Years
Item
Alter mindestens 18 Jahre
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
Biopsy proven mantle cell lymphoma
Item
Biopsy proven mantle cell lymphoma
boolean
C0005558 (UMLS CUI 2011AA)
86273004 (SNOMED CT 2011_0131)
10004720 (MedDRA 14.1)
MTHU028106 (LOINC Version 232)
C0456369 (UMLS CUI 2011AA)
277025001 (SNOMED CT 2011_0131)
C0334634 (UMLS CUI 2011AA)
443487006 (SNOMED CT 2011_0131)
10061275 (MedDRA 14.1)
C83.1 (ICD-10-CM Version 2010)
200.4 (ICD-9-CM Version 2011)
C0011900 (UMLS CUI 2011AA)
439401001 (SNOMED CT 2011_0131)
MTHU008876 (LOINC Version 232)
Patients who have progressed or relapsed after or are refractory to at least one, and up to three prior chemotherapy regimens, and who have documented progressive disease.
Item
Patients who have progressed or relapsed after or are refractory to at least one, and up to three prior chemotherapy regimens, and who have documented progressive disease.
boolean
C0242656 (UMLS CUI 2011AA)
246453008 (SNOMED CT 2011_0131)
10061818 (MedDRA 14.1)
C0277556 (UMLS CUI 2011AA)
58184002 (SNOMED CT 2011_0131)
C0205269 (UMLS CUI 2011AA)
20646008 (SNOMED CT 2011_0131)
C1514457 (UMLS CUI 2011AA)
C1301725 (UMLS CUI 2011AA)
397934002 (SNOMED CT 2011_0131)
C1335499 (UMLS CUI 2011AA)
ECOG performance score 0,1, or 2
Item
ECOG performance score 0,1, or 2
boolean
C1520224 (UMLS CUI 2011AA)
Willing to follow pregnancy precaution
Item
Willing to follow pregnancy precaution
boolean
C0600109 (UMLS CUI 2011AA)
225466006 (SNOMED CT 2011_0131)
C0032961 (UMLS CUI 2011AA)
289908002 (SNOMED CT 2011_0131)
10036556 (MedDRA 14.1)
MTHU035048 (LOINC Version 232)
C1882442 (UMLS CUI 2011AA)
Any of the following laboratory abnormalities
Item
abnormale Laborbefunde
boolean
C0438215 (UMLS CUI 2011AA)
165346000 (SNOMED CT 2011_0131)
10023547 (MedDRA 14.1)
Absolute neutrophil count (ANC)<1,500 cells/mm^3 (1.5 x 10^9/L)
Item
Absolute Neutrophil Count, ANC
boolean
C0948762 (UMLS CUI 2011AA)
10052033 (MedDRA 14.1)
Platelet count < 60,000/mm^3 (60 x 10^9/L)
Item
Thrombozyten
boolean
C1287267 (UMLS CUI 2011AA)
365632008 (SNOMED CT 2011_0131)
777-3 (LOINC Version 232)
Serum aspartate transaminase (AST/SGOT) or alanine transaminase (ALT/SGPT) >3.0 x upper limit or normal (ULN), except patients with documented liver involvement by lymphoma
Item
Serum aspartate transaminase (AST/SGOT) or alanine transaminase (ALT/SGPT) >3.0 x upper limit or normal (ULN), except patients with documented liver involvement by lymphoma
boolean
C0004002 (UMLS CUI 2011AA)
26091008 (SNOMED CT 2011_0131)
MTHU004883 (LOINC Version 232)
C0001899 (UMLS CUI 2011AA)
56935002 (SNOMED CT 2011_0131)
MTHU006766 (LOINC Version 232)
C1519815 (UMLS CUI 2011AA)
C1554961 (UMLS CUI 2011AA)
E (HL7 V3 2006_05)
C0441932 (UMLS CUI 2011AA)
258322007 (SNOMED CT 2011_0131)
C0024299 (UMLS CUI 2011AA)
21964009 (SNOMED CT 2011_0131)
10025310 (MedDRA 14.1)
C85.9 (ICD-10-CM Version 2010)
Serum total bilirubin > 1.5 x ULN, except in case of Gilbert's Syndrome and documented liver involvement by lymphoma.
Item
Serum total bilirubin > 1.5 x ULN, except in case of Gilbert's Syndrome and documented liver involvement by lymphoma.
boolean
C1278039 (UMLS CUI 2011AA)
313840000 (SNOMED CT 2011_0131)
10040162 (MedDRA 14.1)
C1519815 (UMLS CUI 2011AA)
C1554961 (UMLS CUI 2011AA)
E (HL7 V3 2006_05)
C0017551 (UMLS CUI 2011AA)
27503000 (SNOMED CT 2011_0131)
10018267 (MedDRA 14.1)
E80.4 (ICD-10-CM Version 2010)
C0441932 (UMLS CUI 2011AA)
258322007 (SNOMED CT 2011_0131)
C0024299 (UMLS CUI 2011AA)
21964009 (SNOMED CT 2011_0131)
10025310 (MedDRA 14.1)
C85.9 (ICD-10-CM Version 2010)
Calculated creatinine clearance (Cockcroft-Gault formula) of < 30 mL/min
Item
Estimation of creatinine clearance by Cockcroft-Gault formula (procedure)
boolean
C2711451 (UMLS CUI 2011AA)
442407001 (SNOMED CT 2011_0131)
History of active CNS lymphoma within the previous 3 months
Item
History of active CNS lymphoma within the previous 3 months
boolean
CL421546 (UMLS CUI 2011AA)
392521001 (SNOMED CT 2011_0131)
C0205177 (UMLS CUI 2011AA)
55561003 (SNOMED CT 2011_0131)
C0280803 (UMLS CUI 2011AA)
307649006 (SNOMED CT 2011_0131)
10007953 (MedDRA 14.1)
200.5 (ICD-9-CM Version 2011)
Subjects not willing to take DVT prophylaxis
Item
Subjects not willing to take DVT prophylaxis
boolean
C1518422 (UMLS CUI 2011AA)
C0600109 (UMLS CUI 2011AA)
225466006 (SNOMED CT 2011_0131)
C0853245 (UMLS CUI 2011AA)
10013880 (MedDRA 14.1)
Known seropositive for or active viral infection with human immunodeficiency virus (HIV), hepatitis B virus (HBV) or hepatitis C virus (HCV). Patients who are sero-positive because of hepatitis B virus vaccine are eligible
Item
Known seropositive for or active viral infection with human immunodeficiency virus (HIV), hepatitis B virus (HBV) or hepatitis C virus (HCV). Patients who are sero-positive because of hepatitis B virus vaccine are eligible
boolean
C0521143 (UMLS CUI 2011AA)
4879001 (SNOMED CT 2011_0131)
C0205177 (UMLS CUI 2011AA)
55561003 (SNOMED CT 2011_0131)
C0042769 (UMLS CUI 2011AA)
34014006 (SNOMED CT 2011_0131)
10047461 (MedDRA 14.1)
B34.9 (ICD-10-CM Version 2010)
C0019682 (UMLS CUI 2011AA)
19030005 (SNOMED CT 2011_0131)
C0019169 (UMLS CUI 2011AA)
81665004 (SNOMED CT 2011_0131)
C0220847 (UMLS CUI 2011AA)
62944002 (SNOMED CT 2011_0131)
10019752 (MedDRA 14.1)
C1548635 (UMLS CUI 2011AA)
ELG (HL7 V3 2006_05)
C0521143 (UMLS CUI 2011AA)
4879001 (SNOMED CT 2011_0131)
CL420107 (UMLS CUI 2011AA)
C0062527 (UMLS CUI 2011AA)
396424005 (SNOMED CT 2011_0131)
45 (HL7 V3 2006_05)